日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Praziquantel ameliorates leflunomide-induced nephrotoxicity in mice: a novel therapeutic approach targeting TGF-β/Smad/Wnt/β-catenin/NF-κB/PPAR-γ signaling and Nrf-2

吡喹酮可减轻来氟米特诱导的小鼠肾毒性：一种靶向TGF-β/Smad/Wnt/β-catenin/NF-κB/PPAR-γ信号通路和Nrf-2的新型治疗方法

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04920-3
Elkady, Weam A; Faheem, Safaa A; Hazem, Reem M; El-Orabi, Naglaa F
TGF-β
NF-κB
信号转导
Wnt/β-Catenin
毒理研究
发表日期：2026
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Mitigating Methotrexate-Induced Kidney Damage in Mice by the Phragmanthera austroarabica Extract, Its Major Constituent, and Its Polymeric Nanoparticles

Phragmanthera austroarabica提取物、其主要成分及其聚合物纳米颗粒减轻甲氨蝶呤诱导的小鼠肾损伤

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c06335
Hal, Dina M; Mehanna, Eman T; Hazem, Reem M; Swidan, Shady; Elrayess, Ranwa A; Nashawi, Asma Ahmad; Murshid, Samar S A; Lashkar, Manar O; Elhady, Sameh S; Badr, Jihan M; Fattah, Shaimaa A
毒理研究
肾损伤
发表日期：2025
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Sinapic Acid Ameliorates Cadmium-Induced Hepatotoxicity: Modulation of Oxidative Stress, Inflammation, and Apoptosis.

芥子酸可改善镉诱导的肝毒性：调节氧化应激、炎症和细胞凋亡

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13051065
Farahat Yomna A, El-Sayed Norhan M, Hazem Reem M, Mehanna Eman T, Radwan Asmaa
细胞生物学
凋亡
氧化应激
炎症
发表日期：2025
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Cytotoxic and proapoptotic effects of alizarin in mice with Ehrlich solid tumor: novel insights into ERα-mediated MDM2/p-Rb/E2F1 signaling pathway

茜素对艾氏实体瘤小鼠的细胞毒性和促凋亡作用：ERα介导的MDM2/p-Rb/E2F1信号通路的新见解

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04196-7
Eid, Aya H; Al-Karmalawy, Ahmed A; Abdelhameed, Reda F A; Mostafa, Yasser M; Helal, Gouda K; Mehanna, Eman T; Hazem, Reem M
凋亡
表观遗传
信号转导
MDM2
E2F1
细胞生物学
毒理研究
发表日期：2025
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Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders

开发、生物学评价和分子建模一些苯磺酰胺衍生物作为蛋白酪氨酸磷酸酶-1B抑制剂，用于治疗糖尿病及相关代谢紊乱

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d4md00594e
Ghareb, Nagat; Darwish, Khaled M; Nafie, Mohamed S; Elrayess, Ranwa; Abourobe, Noha M; Fattah, Shaimaa A; Hazem, Reem M; Mehanna, Eman T; Elrayess, Ranza
糖尿病
代谢
发表日期：2024
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