日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of Sovleplenib, a Selective Inhibitor of Syk in Clinical Development for Autoimmune Diseases and Cancers

Sovleplenib 的发现：一种选择性 Syk 抑制剂，目前正处于治疗自身免疫性疾病和癌症的临床开发阶段

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00553
Jia, Hong; Deng, Wei; Hao, Baoyu; Cai, Min; Guo, Dong; Cai, Yu; Dai, Xiaoming; Wu, Zhipeng; He, Weigang; Wang, Jian; Wang, Guanglin; Xia, Sumei; Li, Na; Su, Weiguo; Dai, Guangxiu
自身免疫性疾病
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2024
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Withdrawal: The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway

撤退：溶酶体相关凋亡诱导蛋白（LAPF）含有pleckstrin同源结构域（PH）和FYVE结构域，代表了一类新型的含PH和FYVE结构域蛋白，它通过溶酶体-线粒体途径诱导不依赖于caspase的细胞凋亡。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2021.100764
Chen, Wei; Li, Nan; Chen, Taoyong; Han, Yanmei; Li, Changfei; Wang, Yuzhen; He, Weigang; Zhang, Lihuang; Wan, Tao; Cao, Xuetao
细胞生物学
凋亡
线粒体
表观遗传
发表日期：2021
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MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation.

MCL通过抑制NF-κB和NLRP3炎症小体的激活，在结核分枝杆菌诱导的免疫反应中发挥抗炎作用

期刊:Mediators of Inflammation
影响因子:4.2
doi:10.1155/2017/2432904
Zhang Qingwen, Jiang Xinru, He Weigang, Wei Kailin, Sun Jinxia, Qin Xiangyang, Zheng Yuejuan, Jiang Xin
炎症/感染
炎性小体
炎症
发表日期：2017
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Micheliolide provides protection of mice against Staphylococcus aureus and MRSA infection by down-regulating inflammatory response.

米歇利醇通过下调炎症反应，保护小鼠免受金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌感染

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep41964
Jiang Xinru, Wang Yuli, Qin Yifei, He Weigang, Benlahrech Adel, Zhang Qingwen, Jiang Xin, Lu Zhenhui, Ji Guang, Zheng Yuejuan
炎症/感染
炎症
发表日期：2017
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