日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

KDM5B-driven glucose metabolic reprogramming promotes enzalutamide resistance in prostate cancer via the lactate/hnRNPA1 lactylation/AR-V7 axis.

KDM5B 驱动的葡萄糖代谢重编程通过乳酸/hnRNPA1 乳酸化/AR-V7 轴促进前列腺癌对恩扎卢胺的耐药性。

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-026-02602-z
Sun Rui, Huang Yong, He Hao, Li Qiuchen, Wang Linfeng, Zhang Gaojie, Wei Ziling, Cao Yang, Li Jing, Wang Xianmin, Yang Fan, Chen Wenjun, Li Xiang, Yu Jiang, Liu Siyuan, Lei Congfeng, Jiang Yu, Peng Yueqiang, Su Huiyi, Gao Yingying, He Weiyang, Yang Lei, Liu Jiayu
前列腺癌
代谢
KDM5B
乳酸化
代谢重编程
发表日期：2026
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Commentary on "Complex causal association between immune cell phenotypes and bladder cancer: a Mendelian randomization and mediation study"

对“免疫细胞表型与膀胱癌之间复杂的因果关系：孟德尔随机化和中介研究”的评论

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000003587
Tong, Hang; Sun, Yan; He, Weiyang
肿瘤
肿瘤免疫
细胞生物学
膀胱癌
免疫/内分泌
发表日期：2026
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Deep learning for prognostic stratification and biomarker exploration in upper tract urothelial carcinoma: a multicenter retrospective cohort study

深度学习在上尿路尿路上皮癌预后分层和生物标志物探索中的应用：一项多中心回顾性队列研究

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000003581
Peng, Xiang; Tan, Hao; Xiao, Bangxin; Tan, Yiwen; Yue, Xiaofeng; Cao, Youde; Liang, Bing; Zhao, Wenlong; Liu, Yingjia; He, Quanhao; He, Weiyang; Xiao, Mingzhao
肿瘤
肿瘤免疫
发表日期：2026
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Single-cell transcriptome analysis reveals DNMT1(+) epithelial cells promote lymphatic metastasis via CXCL17-mediated TAM infiltration

单细胞转录组分析揭示DNMT1(+)上皮细胞通过CXCL17介导的TAM浸润促进淋巴转移。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-026-08032-1
Yang, Guo; Liu, Jiayu; Guo, Tingting; Zhu, Junlong; Li, Tinghao; Sun, Yan; Qin, Zijia; Gan, Junlin; Li, Xinyuan; He, Weiyang
上皮细胞
单细胞
DNMT1
CXCL1
细胞生物学
发表日期：2026
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Efficacy of pancreatic enzyme replacement therapy (PERT) in the treatment of gastrointestinal symptoms after gastric cancer surgery: study protocol for a multicenter randomized controlled open-label trial

胰酶替代疗法（PERT）治疗胃癌术后胃肠道症状的疗效：一项多中心随机对照开放标签试验的研究方案

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1779727
Xiao, Shuomeng; Bu, Jun; Wu, Yingxin; Lu, Yaoheng; Zhang, Peng; Liu, Kuan; Zhou, Yulong; Liu, Peng; Zhao, Fazhi; Yang, Chao; Zhou, Da; Chen, Qingchuan; He, Weiyang; Ding, Zhi; Chen, Xiaodong; Zhou, Xiang; Zhao, Ping; Zhou, Huali; Xu, Rui
胃癌
肿瘤
肿瘤免疫
发表日期：2026
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The FN1-ITGB4 Axis Drives Acquired Chemoresistance in Bladder Cancer by Activating FAK Signaling.

FN1-ITGB4轴通过激活FAK信号通路驱动膀胱癌获得性化疗耐药性。

期刊:Oncology Research
影响因子:4.1
doi:10.32604/or.2025.072084
Zhang Xiaoyu, Zong RenFei, Sun Yan, Chen Nan, Zhu Kunyao, Tong Hang, Li Tinghao, Zhu Junlong, Qin Zijia, Wu Linfeng, Wang Aimin, He Weiyang
肿瘤
肿瘤免疫
FAK
信号转导
膀胱癌
发表日期：2026
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RBM11 drives malignant progression of bladder cancer by regulating GNPDA1-PKM2 axis.

RBM11 通过调节 GNPDA1-PKM2 轴驱动膀胱癌的恶性进展。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.115402
Tong Hang, Li Tinghao, Zhu Junlong, Dou Qian, Yu Qiong, Sun Yan, He Weiyang
膀胱癌
肿瘤
发表日期：2026
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Irinotecan alleviates chemoresistance to anthracyclines through the inhibition of AARS1-mediated BLM lactylation and homologous recombination repair.

伊立替康通过抑制 AARS1 介导的 BLM 乳酸化和同源重组修复来缓解蒽环类药物的耐药性

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02302-y
Li Xinyuan, Zhang Chunlin, Mei Yuhua, Zhong Wenlong, Fan Wei, Liu Li, Feng Zhenwei, Bai Xuesong, Liu Chuan, Xiao Mingzhao, He Weiyang, Lin Tianxin, Gou Xin
信号转导
发表日期：2025
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Nucleophosmin 1 lactylation in graft kidney induces ferroptotic trigger waves that exacerbate delayed graft function

移植肾中核磷蛋白1的乳酸化会诱导铁死亡触发波，从而加剧移植肾功能延迟恢复。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66991-3
Yu, Haitao; Yin, Hubin; Mei, Yuhua; Bai, Xuesong; Zhang, Chunlin; Feng, Zhenwei; Li, Mao; Chen, Haonan; Liang, Simin; Gou, Xin; Zhong, Wenlong; He, Weiyang; Li, Jie; Lin, Tianxin; Li, Xinyuan
乳酸化
铁死亡
发表日期：2025
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Prior knowledge-guided multimodal deep learning system for biomarker exploration and prognosis prediction of urothelial carcinoma

基于先验知识引导的多模态深度学习系统用于尿路上皮癌生物标志物探索和预后预测

期刊:npj Digital Medicine
影响因子:15.1
doi:10.1038/s41746-025-02232-7
He, Quanhao; Tan, Hao; Xiao, Bangxin; Tan, Yiwen; Peng, Xiang; Peng, Canjie; Yue, Xiaofeng; Jiang, Linshan; Cao, Youde; Lv, Fa Jin; Zhao, Wenlong; Yi, Hongmei; Liu, YingJia; He, Weiyang; Xiao, Mingzhao
肿瘤
肿瘤免疫
发表日期：2025
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