Reducing PDK4 level constitutes a pivotal mechanism for glucocorticoids to impede osteoblastic differentiation through the enhancement of ferroptosis in mesenchymal stem cells.
降低 PDK4 水平是糖皮质激素通过增强间充质干细胞的铁死亡来抑制成骨细胞分化的关键机制
期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04186-9
Jiang Yue, Ye Ai-Hua, He Wen-Ge, Liu Lu, Gao Xiang, Liu Hang, Liu Wen-Ting, Ye Fang-Lin, He Dong-Mei, Liao Jun-Yi, Wang Jing, He Bai-Cheng