The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway.
石菖蒲挥发油通过抑制 p38 MAPK/NLRP3/STAT3 信号通路，显著减轻了图雷特综合征大鼠模型中的神经炎症损伤。
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1540092
Wei Xing, Sun Kexin, Feng Peng, Huang Shuang, Jiang Bing, Cui Min, Chen Yuanhuan, Xue Fuchun, He Yuezhen, Yao Jingxi, Shang Jing, Mei Hao, Ding Yanqing, Tian Yongyan, Guo Guangyu, Yang Nan, Shi Zhenggang
炎症
p38 MAPK
炎症/感染
信号转导
JAK/STAT
Rat
神经科学
MAPK/ERK
STAT3
LRP3
NLRP3
神经炎症
