日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium

吸入式纳米制剂mRNA多聚体用于肺上皮细胞蛋白质生产

期刊:Advanced Materials
影响因子:26.8
doi:10.1002/adma.201805116
Patel, Asha Kumari; Kaczmarek, James C; Bose, Suman; Kauffman, Kevin J; Mir, Faryal; Heartlein, Michael W; DeRosa, Frank; Langer, Robert; Anderson, Daniel G
上皮细胞
细胞生物学
发表日期：2019
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Improved Efficacy in a Fabry Disease Model Using a Systemic mRNA Liver Depot System as Compared to Enzyme Replacement Therapy

在法布里病模型中，与酶替代疗法相比，使用全身性mRNA肝脏储存系统可提高疗效

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2019.03.001
DeRosa, Frank; Smith, Lianne; Shen, Yinghua; Huang, Yan; Pan, Jing; Xie, Hongsheng; Yahalom, Barak; Heartlein, Michael W
发表日期：2019
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mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo

体内治疗性抗HER2抗体表达的mRNA递送

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2019.05.012
Rybakova, Yulia; Kowalski, Piotr S; Huang, Yuxuan; Gonzalez, John T; Heartlein, Michael W; DeRosa, Frank; Delcassian, Derfogail; Anderson, Daniel G
HER2
发表日期：2019
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Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs

用于递送siRNA和mRNA的可定制脂质纳米颗粒材料

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201809056
Fenton, Owen S; Kauffman, Kevin J; McClellan, Rebecca L; Kaczmarek, James C; Zeng, Manhao D; Andresen, Jason L; Rhym, Luke H; Heartlein, Michael W; DeRosa, Frank; Anderson, Daniel G
发表日期：2018
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Optimization of a Degradable Polymer-Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells

优化可降解聚合物-脂质纳米颗粒以实现mRNA向肺内皮细胞和免疫细胞的有效全身递送

期刊:Nano Letters
影响因子:9.1
doi:10.1021/acs.nanolett.8b02917
Kaczmarek, James C; Kauffman, Kevin J; Fenton, Owen S; Sadtler, Kaitlyn; Patel, Asha K; Heartlein, Michael W; DeRosa, Frank; Anderson, Daniel G
细胞生物学
内皮细胞
免疫/内分泌
发表日期：2018
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Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs

用于将mRNA系统性递送至肺部的聚合物-脂质纳米颗粒

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201608450
Kaczmarek, James C; Patel, Asha K; Kauffman, Kevin J; Fenton, Owen S; Webber, Matthew J; Heartlein, Michael W; DeRosa, Frank; Anderson, Daniel G
发表日期：2016
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Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo

体内脂质纳米颗粒全身递送未修饰和假尿苷修饰的mRNA的疗效和免疫原性

期刊:Biomaterials
影响因子:12.9
doi:10.1016/j.biomaterials.2016.09.006
Kauffman, Kevin J; Mir, Faryal F; Jhunjhunwala, Siddharth; Kaczmarek, James C; Hurtado, Juan E; Yang, Jung H; Webber, Matthew J; Kowalski, Piotr S; Heartlein, Michael W; DeRosa, Frank; Anderson, Daniel G
免疫/内分泌
发表日期：2016
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Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo

聚（糖胺胺）刷配制纳米材料用于体内系统性siRNA和mRNA递送

期刊:Nano Letters
影响因子:9.1
doi:10.1021/acs.nanolett.5b02428
Dong, Yizhou; Dorkin, J Robert; Wang, Weiheng; Chang, Philip H; Webber, Matthew J; Tang, Benjamin C; Yang, Junghoon; Abutbul-Ionita, Inbal; Danino, Dganit; DeRosa, Frank; Heartlein, Michael; Langer, Robert; Anderson, Daniel G
发表日期：2016
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Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

使用生物合成 mRNA 肝库系统对血友病 B 模型的治疗效果

期刊:Gene Therapy
影响因子:4.6
doi:10.1038/gt.2016.46
F DeRosa, B Guild, S Karve, L Smith, K Love, J R Dorkin, K J Kauffman, J Zhang, B Yahalom, D G Anderson, M W Heartlein
信号转导
发表日期：2016
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CNS penetration of intrathecal-lumbar idursulfase in the monkey, dog and mouse: implications for neurological outcomes of lysosomal storage disorder

鞘内腰椎注射艾杜硫酶对猴、狗和小鼠中枢神经系统的渗透：对溶酶体贮积症神经系统预后的影响

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0030341
Calias, Pericles; Papisov, Mikhail; Pan, Jing; Savioli, Nancy; Belov, Vasily; Huang, Yan; Lotterhand, Jason; Alessandrini, Mary; Liu, Nan; Fischman, Alan J; Powell, Jan L; Heartlein, Michael W
神经科学
发表日期：2012
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