日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-Based Design of First-Generation Small Molecule Inhibitors Targeting the Catalytic Pockets of AID, APOBEC3A, and APOBEC3B

基于结构的第一代小分子抑制剂设计,靶向 AID、APOBEC3A 和 APOBEC3B 的催化口袋

Justin J King, Faezeh Borzooee, Junbum Im, Mahdi Asgharpour, Atefeh Ghorbani, Cody P Diamond, Heather Fifield, Lesley Berghuis, Mani Larijani

A licensing step links AID to transcription elongation for mutagenesis in B cells

许可步骤将 AID 与 B 细胞诱变的转录延长联系起来

Stephen P Methot, Ludivine C Litzler, Poorani Ganesh Subramani, Anil K Eranki, Heather Fifield, Anne-Marie Patenaude, Julian C Gilmore, Gabriel E Santiago, Halil Bagci, Jean-François Côté, Mani Larijani, Ramiro E Verdun, Javier M Di Noia

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

激活诱导脱氨酶 C 末端结构域将 DNA 断裂与类别转换重组过程中的末端保护和修复联系起来

Astrid Zahn, Anil K Eranki, Anne-Marie Patenaude, Stephen P Methot, Heather Fifield, Elena M Cortizas, Paul Foster, Kohsuke Imai, Anne Durandy, Mani Larijani, Ramiro E Verdun, Javier M Di Noia