日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Specific depletion of TIGIT(high) CD226(-) clonally expanded intratumoral Tregs defines safe and effective TIGIT targeting

特异性清除肿瘤内克隆扩增的 TIGIT(high)CD226(-)调节性T细胞，是安全有效的TIGIT靶向治疗的关键。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013636
Zhou, Haoyue; Li, Jinmei; Mei, Song; Zhang, Meiyu; Zhao, Haochen; Yan, Kepeng; Cheng, Yumeng; Zhou, Qunmin; Zheng, Pan; Liu, Yang; Zhang, Peng; Li, Hecheng; Lu, Wei; Zhang, Yan
肿瘤
T细胞
肿瘤免疫
CD22
T细胞
TIGIT
细胞生物学
CD2
CD226
免疫/内分泌
发表日期：2026
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Sequential delivery of sinigrin and dabigatran by an in situ self-stabilizing dynamic hydrogel attenuates intervertebral disc degeneration

通过原位自稳定动态水凝胶依次递送芥子苷和达比加群酯可减轻椎间盘退变。

期刊:Materials Today Bio
影响因子:10.2
doi:10.1016/j.mtbio.2026.102827
Hu, Rui; Liu, Kaiwen; Wang, Wenzhao; Zhang, Wencan; Wang, Liang; Zhang, Yuanqiang; Ma, Hecheng; Cong, Menglin; Chi, Chuanxi; Cao, Jiankang; Zhang, Baoliang; Liu, Liang; Meng, Qunbo; Kong, Xiangzhen; Shi, Bin; Li, Liming; Cheng, Lei; Wei, Zhijian
发表日期：2026
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Sesamin exhibits potential food-drug interactions through the inhibition of cytochrome P450s and human UDP-glucuronosyltransferases in vitro

芝麻素可通过体外抑制细胞色素P450和人UDP-葡萄糖醛酸转移酶而表现出潜在的食物-药物相互作用。

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d6ra00237d
Yin, Hang; Zhu, Lei; Wang, Xiaoyu; Wang, Zhen; Wang, Hecheng; Liu, Yong
细胞生物学
发表日期：2026
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CD4(+)CXCL13(+) exhausted T cells drive immune microenvironment divergence in synchronous double primary lung adenocarcinoma with different degrees of invasiveness.

CD4(+)CXCL13(+)耗竭的T细胞驱动不同侵袭程度的同步双原发性肺腺癌的免疫微环境分化。

期刊:Translational Lung Cancer Research
影响因子:3.5
doi:10.21037/tlcr-2025-1-1489
Chen Xueyu, Zhang Jiahao, Lu Tong, Du Mingyuan, Li Fangyuan, Dong Dong, Cao Yuqin, Zhang Yajie, Li Hecheng
肿瘤
T细胞
肿瘤免疫
CXCL1
CXCL13
T细胞
细胞生物学
CD4
免疫/内分泌
发表日期：2026
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Clinical-Radiomics Signature Predicts Pathologic Complete Response After Neoadjuvant Therapy in Oesophageal Squamous Cell Carcinoma

临床放射组学特征预测食管鳞状细胞癌新辅助治疗后的病理完全缓解

期刊:Interdisciplinary Cardiovascular and Thoracic Surgery
影响因子:1.3
doi:10.1093/icvts/ivag024
Shi, Liqiang; Wang, Xipeng; Chen, Xueyu; Cao, Yuqin; Li, Chengqiang; Bai, Yaya; Cheng, Zenghui; Dong, Dong; Chen, Xiaoyan; Zhang, Yajie; Li, Hecheng
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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Robotic-assisted bronchoscopy in dye localization in thoracoscopic pulmonary nodule resection: An initial experience

机器人辅助支气管镜在胸腔镜肺结节切除术中染料定位的应用：初步经验

期刊:
影响因子:
doi:10.1016/j.xjtc.2026.102272
Wang, Xinyi; Ma, Jiajun; She, Wenbo; Chen, Fang; Liao, Hongen; Han, Dingpei; Li, Hecheng
发表日期：2026
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Preoperative pembrolizumab (anti-PD-1 antibody) combined with chemoradiotherapy for esophageal squamous cell carcinoma: a phase 1/2 trial (PALACE-2)

术前帕博利珠单抗（抗PD-1抗体）联合放化疗治疗食管鳞状细胞癌：一项1/2期试验（PALACE-2）

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02477-4
Li, Chengqiang; Han, Yichao; Zhao, Shengguang; Kang, Xiaozheng; Zheng, Yuyan; Cao, Yuqin; Yan, Yan; Shi, Liqiang; Wang, Xipeng; Lu, Tong; Zou, Guowen; Li, Huan; Che, Jiaming; Xiang, Jie; Zhu, Lianggang; Hang, Junbiao; Zhang, Yajie; Jin, Runsen; Han, Dingpei; Chen, Xueyu; Jing, Hui; Guo, Wei; Cheng, Zenghui; Zhao, Liqin; Chen, Xiaoyan; Yu, Bentong; Li, Jian; Li, Bin; Li, Yin; Li, Hecheng
细胞生物学
肿瘤
肿瘤免疫
PD-1
发表日期：2025
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PIEZO1 mediates mechanical reprogramming of neutrophils for proangiogenic specialization in the lung

PIEZO1介导中性粒细胞的机械重编程，使其在肺部分化为促血管生成细胞

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI183796
Jin Wang ，Wenying Zhao ，Wenjuan Bai ，Dong Dong ，Hui Wang ，Xin Qi ，Ajitha Thanabalasuriar ，Youqiong Ye ，Tian-le Xu ，Hecheng Li ，Paul Kubes ，Bin Li ，Jing Wang
ZO1
细胞生物学
血管生成
中性粒细胞
粒细胞
发表日期：2025
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Periventricular diffusivity reflects APOE ε4-modulated amyloid accumulation and cognitive impairment in the Alzheimer's disease continuum

脑室周围扩散率反映了APOE ε4调控的淀粉样蛋白积累和阿尔茨海默病连续谱中的认知障碍。

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.70659
Chen, Chang-Le; Son, Sang Joon; Schweitzer, Noah; Jin, Hecheng; Li, Jinghang; Wang, Linghai; Yang, Shaolin; Hong, Chang Hyung; Roh, Hyun Woong; Park, Bumhee; Choi, Jin Wook; An, Young-Sil; Seo, Sang Woon; Cho, Yong Hyuk; Hong, Sunhwa; Nam, You Jin; Minhas, Davneet S; Laymon, Charles M; Stetten, George D; Tudorascu, Dana L; Aizenstein, Howard J; Wu, Minjie
信号转导
阿尔茨海默症
APOE
神经科学
发表日期：2025
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Circulating tumor DNA as a biomarker for progression and survival in esophageal cancer after neoadjuvant therapy and esophagectomy: a systematic review and meta-analysis

循环肿瘤DNA作为食管癌新辅助治疗和食管切除术后进展和生存的生物标志物：系统评价和荟萃分析

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000003017
Shen, Tianzheng; Li, Tiancheng; Cao, Yuqin; Zhang, Yajie; Li, Hecheng
食管癌
肿瘤
肿瘤免疫
发表日期：2025
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