日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight

早期NK细胞和T细胞功能障碍标志着肥胖和体重正常的登革热患者病情进展为重症。

Gregorova, Michaela; Santopaolo, Marianna; Garner, Lucy C; Hayati, Rahma F; Diamond, Divya; Ramamurthy, Narayan; Tran, Vi Thuy; Nguyen, Nguyet Minh; Heesom, Kate J; Nguyen, Vuong Lam; Jones, Eben; Nsubuga, Mike; Luscombe, Curtis; Vo, Hoa Thi My; Ho, Chanh Quang; Nguyen, Chau Thi Xuan; Dong, Tam Thi Hoai; Huynh, Duyen Thi Le; Cao, Tam Thi; Davidson, Andrew D; Klenerman, Paul; Yacoub, Sophie; Rivino, Laura

Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation.

内体邻近蛋白质组的绘制揭示了 Retromer 是 RAB GTPase 调控的枢纽

Antón-Plágaro Carlos, Chen Kai-En, Guo Qian, Liu Meihan, Evans Ashley J, Lewis Philip A, Heesom Kate J, Wilkinson Kevin A, Collins Brett M, Cullen Peter J

Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7

RAB32-LRMDA-Commander膜转运复合物的鉴定揭示了人类7型眼皮肤白化病的分子机制

Rebeka Butkovič ,Michael D Healy ,Cecilia de Heus ,Alexander P Walker ,Wyatt Beyers ,Kerrie E McNally ,Philip A Lewis ,Kate J Heesom ,Nalan Liv ,Judith Klumperman ,Santiago Di Pietro ,Brett M Collins ,Peter J Cullen

An extended network for regulation of heme homeostasis in cells

细胞内血红素稳态调控的扩展网络

Gallio, Andrea E; Marson, Noa A; Heesom, Kate J; Lewis, Philip A; Alibhai, Dominic; Dugdale, Celyn A; Herman, Andrew; Basran, Jaswir; Hudson, Andrew J; Raven, Emma L

Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.

通过自身抑制鉴定出与 Retriever 和 Retromer 辅助蛋白结合受限的 VPS29 同工型

Daly James L, Chen Kai-En, Butkovič Rebeka, Guo Qian, Healy Michael D, Pennink Eva, Gamble-Strutt Georgia, Higham Zara, Moody Edmund R R, Lewis Philip A, Heesom Kate J, Williams Tom A, McMillan Kirsty J, Collins Brett M, Cullen Peter J

Multiple golgins are required to support extracellular matrix secretion, modification, and assembly.

多种高尔基体蛋白共同作用,支持细胞外基质的分泌、修饰和组装

Thompson George, Hoyle Anna, Lewis Philip A, Prada-Sanchez M Esther, Swift Joe, Heesom Kate, Lowe Martin, Stephens David, Stevenson Nicola L

A Novel Role of Hyaluronan and Its Membrane Receptors, CD44 and RHAMM, in Obesity-Related Kidney Pathology.

透明质酸及其膜受体 CD44 和 RHAMM 在肥胖相关肾脏病理中的新作用。

Qi Bingxue, Musale Vishal, Weng Xiong, Banah Ayman K, Lawlor Alexander, Murdoch Colin E, Lay Abigail C, Heesom Kate J, Coward Richard J M, O'Connor Christopher L, Ju Wenjun, Bitzer Markus, Hills Claire E, Chen Yang, Kang Li

Failed induction of human labour is associated with an altered myometrial phosphoproteome

人类引产失败与子宫肌层磷酸化蛋白质组的改变有关。

Birchenall, Katherine Alice; Hudson, Claire; Lewis, Philip A; Bahl, Rachna; Quinn, Sarah; Heesom, Kate; Welsh, Gavin Iain; López Bernal, Andrés

Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7

RAB32-LRMDA-Commander 膜运输复合物的鉴定揭示了人类眼皮肤白化病 7 型的分子机制

Rebeka Butkovič, Michael D Healy, Cecilia de Heus, Alexander P Walker, Wyatt Beyers, Kerrie E McNally, Philip A Lewis, Kate J Heesom, Nalan Liv, Judith Klumperman, Santiago Di Pietro, Brett M Collins, Peter J Cullen

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease

对胰岛素抵抗肾脏模型和人类活检样本的分析揭示了糖尿病肾病的共同机制和细胞类型特异性机制。

Lay, Abigail C; Tran, Van Du T; Nair, Viji; Betin, Virginie; Hurcombe, Jennifer A; Barrington, Alexandra F; Pope, Robert Jp; Burdet, Frédéric; Mehl, Florence; Kryvokhyzha, Dmytro; Ahmad, Abrar; Sinton, Matthew C; Lewis, Philip; Wilson, Marieangela C; Menon, Rajasree; Otto, Edgar; Heesom, Kate J; Ibberson, Mark; Looker, Helen C; Nelson, Robert G; Ju, Wenjun; Kretzler, Matthias; Satchell, Simon C; Gomez, Maria F; Coward, Richard J M