日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7

RAB32-LRMDA-Commander膜转运复合物的鉴定揭示了人类7型眼皮肤白化病的分子机制

Butkovič, Rebeka; Healy, Michael D; de Heus, Cecilia; Walker, Alexander P; Beyers, Wyatt; McNally, Kerrie E; Lewis, Philip A; Heesom, Kate J; Liv, Nalan; Klumperman, Judith; Di Pietro, Santiago; Collins, Brett M; Cullen, Peter J

Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight

早期NK细胞和T细胞功能障碍标志着肥胖和体重正常的登革热患者病情进展为重症。

Gregorova, Michaela; Santopaolo, Marianna; Garner, Lucy C; Hayati, Rahma F; Diamond, Divya; Ramamurthy, Narayan; Tran, Vi Thuy; Nguyen, Nguyet Minh; Heesom, Kate J; Nguyen, Vuong Lam; Jones, Eben; Nsubuga, Mike; Luscombe, Curtis; Vo, Hoa Thi My; Ho, Chanh Quang; Nguyen, Chau Thi Xuan; Dong, Tam Thi Hoai; Huynh, Duyen Thi Le; Cao, Tam Thi; Davidson, Andrew D; Klenerman, Paul; Yacoub, Sophie; Rivino, Laura

Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation.

内体邻近蛋白质组的绘制揭示了 Retromer 是 RAB GTPase 调控的枢纽

Antón-Plágaro Carlos, Chen Kai-En, Guo Qian, Liu Meihan, Evans Ashley J, Lewis Philip A, Heesom Kate J, Wilkinson Kevin A, Collins Brett M, Cullen Peter J

An extended network for regulation of heme homeostasis in cells

细胞内血红素稳态调控的扩展网络

Gallio, Andrea E; Marson, Noa A; Heesom, Kate J; Lewis, Philip A; Alibhai, Dominic; Dugdale, Celyn A; Herman, Andrew; Basran, Jaswir; Hudson, Andrew J; Raven, Emma L

Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.

通过自身抑制鉴定出与 Retriever 和 Retromer 辅助蛋白结合受限的 VPS29 同工型

Daly James L, Chen Kai-En, Butkovič Rebeka, Guo Qian, Healy Michael D, Pennink Eva, Gamble-Strutt Georgia, Higham Zara, Moody Edmund R R, Lewis Philip A, Heesom Kate J, Williams Tom A, McMillan Kirsty J, Collins Brett M, Cullen Peter J

A Novel Role of Hyaluronan and Its Membrane Receptors, CD44 and RHAMM, in Obesity-Related Kidney Pathology.

透明质酸及其膜受体 CD44 和 RHAMM 在肥胖相关肾脏病理中的新作用。

Qi Bingxue, Musale Vishal, Weng Xiong, Banah Ayman K, Lawlor Alexander, Murdoch Colin E, Lay Abigail C, Heesom Kate J, Coward Richard J M, O'Connor Christopher L, Ju Wenjun, Bitzer Markus, Hills Claire E, Chen Yang, Kang Li

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease

对胰岛素抵抗肾脏模型和人类活检样本的分析揭示了糖尿病肾病的共同机制和细胞类型特异性机制。

Lay, Abigail C; Tran, Van Du T; Nair, Viji; Betin, Virginie; Hurcombe, Jennifer A; Barrington, Alexandra F; Pope, Robert Jp; Burdet, Frédéric; Mehl, Florence; Kryvokhyzha, Dmytro; Ahmad, Abrar; Sinton, Matthew C; Lewis, Philip; Wilson, Marieangela C; Menon, Rajasree; Otto, Edgar; Heesom, Kate J; Ibberson, Mark; Looker, Helen C; Nelson, Robert G; Ju, Wenjun; Kretzler, Matthias; Satchell, Simon C; Gomez, Maria F; Coward, Richard J M

Improving nitrofurantoin resistance prediction in Escherichia coli from whole-genome sequence by integrating NfsA/B enzyme assays

通过整合NfsA/B酶活性检测,提高基于全基因组序列的大肠杆菌呋喃妥因耐药性预测能力

Dulyayangkul, Punyawee; Sealey, Jordan E; Lee, Winnie W Y; Satapoomin, Naphat; Reding, Carlos; Heesom, Kate J; Williams, Philip B; Avison, Matthew B

Crosstalk between β-catenin and WT1 signaling activity in acute myeloid leukemia

急性髓系白血病中β-catenin和WT1信号活性之间的相互作用

Wagstaff, Megan; Tsaponina, Olga; Caalim, Gilian; Greenfield, Hayley; Milton-Harris, Leanne; Mancini, Erika J; Blair, Allison; Heesom, Kate J; Tonks, Alex; Darley, Richard L; Roberts, Stefan G; Morgan, Rhys G

Characterizing the urinary proteome of prematurity-associated lung disease in school-aged children

对学龄儿童早产相关肺部疾病的尿液蛋白质组进行表征

Course, Christopher W; Lewis, Philip A; Kotecha, Sarah J; Cousins, Michael; Hart, Kylie; Watkins, W John; Heesom, Kate J; Kotecha, Sailesh