Heffern相关文献与解析，生知库 | 链接生命科学的每一步

Vanderschoot, Kyle A; Padilla, Jacob P; Steineman, Kelli A; De Caro, Christopher M; Wang, Yongheng; Wang, Aijun; Heffern, Marie C; Neumann, Elizabeth K

空间多组学

多发性硬化症

发表日期：2026

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High glucose diet induces hepatic iron overload contributing to metabolic dysfunction.

高糖饮食会诱发肝脏铁过载，从而导致代谢功能障碍。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.114441

Caceres Amanda, Harder Nathaniel H O, Padilla Jacob P, Janisse Samuel E, Cole Austin M, Roedersheimer Sonia E, Heffern Marie C

代谢

发表日期：2026

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Inactivation of Atp7b Copper Transporter in Intestinal Epithelial Cells Is Associated with Altered Lipid Processing and Cell Growth Machinery Independent from Hepatic Copper Accumulation and Severity of Liver Histology

肠上皮细胞中Atp7b铜转运蛋白的失活与脂质加工和细胞生长机制的改变有关，且与肝脏铜积累和肝脏组织学严重程度无关。

期刊:American Journal of Pathology

影响因子:3.6

doi:10.1016/j.ajpath.2025.09.015

Caceres, Amanda; Shibata, Noreene M; Davalos-Gutierrez, Christian D; Sarode, Gaurav V; Hussan, Hisham; Bettencourt, Margarida; Fontes, Adriana; Zischka, Hans; Lutsenko, Svetlana; Heffern, Marie C; Medici, Valentina

Developing A Complex Intervention to Integrate Community Paramedics in GP Out-of-Hours Care in Ireland: A Qualitative Study

在爱尔兰，制定一项综合干预措施，将社区护理人员纳入全科医生非工作时间护理服务：一项定性研究

期刊:HRB Open Research

影响因子:

doi:10.12688/hrbopenres.14246.1

Cunningham, Colette; Masterson, Siobhan; Batt, Alan; Heffern, J D; Knox, Shane; Quinlan, Diarmuid; O'Donnell, Cathal; O'Donnell, Deirdre; Barry, Tomas

发表日期：2026

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Integration of label-free surface enhanced Raman spectroscopy (SERS) of extracellular vesicles (EVs) with Raman tagged labels to enhance ovarian cancer diagnostics

将无标记表面增强拉曼光谱（SERS）与拉曼标记相结合，用于增强细胞外囊泡（EVs）的诊断，以提高卵巢癌的诊断能力。

期刊:Biosensors & Bioelectronics

影响因子:10.5

doi:10.1016/j.bios.2025.117800

He, Qing; Koster, Hanna J; O'Sullivan, Justin; Ono, Samantha G; O'Toole, Hannah J; Leiserowitz, Gary S; Heffern, Marie C; Carney, Randy P

Enrichment and functional characterization of copper-binding peptides from food hydrolysates.

食品水解物中铜结合肽的富集和功能表征

期刊:RSC Advances

影响因子:4.6

doi:10.1039/d5ra05166e

Fernandez Rebeca L, Lee Vanessa J, Janisse Samuel E, O'Sullivan Justin J, Caceres Amanda, Heffern Marie C

发表日期：2025

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Computational Spectroscopy Studies of Model Ternary Complexes of Copper(II), C-Peptide, and Serum Albumin Using Excited State-Targeted Geometry Optimization

利用激发态靶向几何优化方法对铜(II)、C肽和血清白蛋白的三元模型配合物进行计算光谱学研究

期刊:Biochemistry

影响因子:3

doi:10.1021/acs.biochem.5c00241

He, Zhecheng; Fernandez, Rebeca L; Heffern, Marie C; Wang, Lee-Ping

发表日期：2025

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Directional selection failed to produce changes in olfactory Y-maze learning and memory but induced changes in climbing phenotypes

定向选择未能改变嗅觉Y迷宫学习和记忆能力，但诱导了攀爬表型的改变。

期刊:

影响因子:

doi:10.1101/2025.05.18.654242

Hamlin, Victoria L; Baumann, Jamie; Heffern, Reiley; Franke, Alaina; King, Elizabeth G

发表日期：2025

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Plant-derived chelators and ionophores as potential therapeutics for metabolic diseases

植物来源的螯合剂和离子载体作为代谢疾病的潜在治疗药物

期刊:Chemical Society Reviews

影响因子:39

doi:10.1039/d3cs00167a

Lee, Vanessa J; Janisse, Samuel E; Heffern, Marie C

代谢

发表日期：2023

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The role of intestine in metabolic dysregulation in murine Wilson disease

肠道在小鼠威尔逊病代谢紊乱中的作用

期刊:Hepatology Communications

影响因子:4.6

doi:10.1097/HC9.0000000000000247

Sarode, Gaurav V; Mazi, Tagreed A; Neier, Kari; Shibata, Noreene M; Jospin, Guillaume; Harder, Nathaniel H O; Caceres, Amanda; Heffern, Marie C; Sharma, Ashok K; More, Shyam K; Dave, Maneesh; Schroeder, Shannon M; Wang, Li; LaSalle, Janine M; Lutsenko, Svetlana; Medici, Valentina

代谢

发表日期：2023

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Spatial Multiomics Combining Lipids and Gene Expression Using MALDI ISH MSI

利用MALDI ISH MSI技术进行脂质和基因表达的空间多组学分析

High glucose diet induces hepatic iron overload contributing to metabolic dysfunction.

高糖饮食会诱发肝脏铁过载，从而导致代谢功能障碍。

Inactivation of Atp7b Copper Transporter in Intestinal Epithelial Cells Is Associated with Altered Lipid Processing and Cell Growth Machinery Independent from Hepatic Copper Accumulation and Severity of Liver Histology

肠上皮细胞中Atp7b铜转运蛋白的失活与脂质加工和细胞生长机制的改变有关，且与肝脏铜积累和肝脏组织学严重程度无关。

Developing A Complex Intervention to Integrate Community Paramedics in GP Out-of-Hours Care in Ireland: A Qualitative Study

在爱尔兰，制定一项综合干预措施，将社区护理人员纳入全科医生非工作时间护理服务：一项定性研究

Integration of label-free surface enhanced Raman spectroscopy (SERS) of extracellular vesicles (EVs) with Raman tagged labels to enhance ovarian cancer diagnostics

将无标记表面增强拉曼光谱（SERS）与拉曼标记相结合，用于增强细胞外囊泡（EVs）的诊断，以提高卵巢癌的诊断能力。

Enrichment and functional characterization of copper-binding peptides from food hydrolysates.

食品水解物中铜结合肽的富集和功能表征

Computational Spectroscopy Studies of Model Ternary Complexes of Copper(II), C-Peptide, and Serum Albumin Using Excited State-Targeted Geometry Optimization

利用激发态靶向几何优化方法对铜(II)、C肽和血清白蛋白的三元模型配合物进行计算光谱学研究

Directional selection failed to produce changes in olfactory Y-maze learning and memory but induced changes in climbing phenotypes

定向选择未能改变嗅觉Y迷宫学习和记忆能力，但诱导了攀爬表型的改变。

Plant-derived chelators and ionophores as potential therapeutics for metabolic diseases

植物来源的螯合剂和离子载体作为代谢疾病的潜在治疗药物

The role of intestine in metabolic dysregulation in murine Wilson disease

肠道在小鼠威尔逊病代谢紊乱中的作用