日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of N-Nitrosamines

调整预孵育条件以增强Ames试验检测N-亚硝胺致突变性的能力

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.70041
Bishop, Michelle E; Sims, Audrey M; Guerrero, Sharon K; Mitchell, Kamela; Mei, Nan; Xu, Hannah; Kruhlak, Naomi L; King, Sruthi T; Dorsam, Robert T; Atrakchi, Aisar H; McGovern, Timothy J; Heflich, Robert H
毒理研究
发表日期：2026
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Comparative DNA damage induced by eight nitrosamines in primary human and macaque hepatocytes

八种亚硝胺对原代人肝细胞和猕猴肝细胞DNA损伤的比较研究

期刊:Chemico-Biological Interactions
影响因子:5.4
doi:10.1016/j.cbi.2025.111538
Seo, Ji-Eun; He, Xiaobo; Bryant, Matthew; Atrakchi, Aisar H; McGovern, Timothy J; Davis Bruno, Karen L; Heflich, Robert H; Guo, Xiaoqing
细胞生物学
毒理研究
发表日期：2025
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Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities

将大鼠肝微核试验整合到 28 天治疗方案中：测试 4 种具有不同致癌效力和肿瘤靶向特异性的小分子亚硝胺的遗传毒性

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfaf002
Guo, Xiaoqing; Seo, Ji-Eun; Xu, Hannah; Yan, Jian; Malhi, Pritpal; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Heflich, Robert H; Chen, Tao
肿瘤
毒理研究
Rat
肿瘤免疫
发表日期：2025
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Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models

利用二维和三维HepaRG细胞模型对十种亚硝胺类药物相关杂质进行遗传毒性评价

期刊:Regulatory Toxicology and Pharmacology
影响因子:3.5
doi:10.1016/j.yrtph.2025.105906
Seo, Ji-Eun; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Keire, David A; Mei, Nan; Heflich, Robert H; Guo, Xiaoqing
细胞生物学
毒理研究
发表日期：2025
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Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)

评估历史阴性对照数据的质量并合理利用这些数据：国际遗传毒性测试研讨会（IWGT）报告

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.22541
Dertinger, Stephen D; Li, Dingzhou; Beevers, Carol; Douglas, George R; Heflich, Robert H; Lovell, David P; Roberts, Daniel J; Smith, Robert; Uno, Yoshifumi; Williams, Andrew; Witt, Kristine L; Zeller, Andreas; Zhou, Changhui
毒理研究
发表日期：2025
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Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model

在人支气管上皮组织模型中表征甲醛烟雾的肺毒性和潜在致突变性

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.70000
Le, Yuan; Ren, Baiping; Muskhelishvili, Levan; Davis, Kelly; Wang, Yiying; Gwinn, William; Rua, Diego; Heflich, Robert H; Cao, Xuefei
Human
毒理研究
发表日期：2025
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Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting

体外浓度-反应数据解读在风险评估和监管决策中的应用：2022年IWGT定量分析专家工作组会议报告

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.22582
Beal, Marc A; Chen, Guangchao; Dearfield, Kerry L; Gi, Min; Gollapudi, Bhaskar; Heflich, Robert H; Horibata, Katsuyoshi; Long, Alexandra S; Lovell, David P; Parsons, Barbara L; Pfuhler, Stefan; Wills, John; Zeller, Andreas; Johnson, George; White, Paul A
发表日期：2025
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Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

关于将突变作为风险评估毒理学终点时效应严重性的考虑：第八届国际遗传毒性测试研讨会（IWGT）报告

期刊:Environmental and Molecular Mutagenesis
影响因子:2.3
doi:10.1002/em.22599
Parsons, Barbara L; Beal, Marc A; Dearfield, Kerry L; Douglas, George R; Gi, Min; Gollapudi, B Bhaskar; Heflich, Robert H; Horibata, Katsuyoshi; Kenyon, Michelle; Long, Alexandra S; Lovell, David P; Lynch, Anthony M; Myers, Meagan B; Pfuhler, Stefan; Vespa, Alisa; Zeller, Andreas; Johnson, George E; White, Paul A
毒理研究
发表日期：2025
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Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen.

人类 HepaRG 细胞长期暴露于基因毒性致癌物后发生突变积累

期刊:Journal of Environmental Science and Health Part C-Toxicology and Carcinogenesis
影响因子:2.3
doi:10.1080/26896583.2025.2548146
Guo Xiaoqing, Seo Ji-Eun, Miranda-Colon Jaime, Xu Hannah, Revollo Javier, Heflich Robert H
细胞生物学
Human
肿瘤免疫
发表日期：2025
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Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

对15种亚硝胺类药物相关杂质在人TK6细胞中的致突变性和遗传毒性进行评价

期刊:Regulatory Toxicology and Pharmacology
影响因子:3.5
doi:10.1016/j.yrtph.2024.105730
Li, Xilin; Le, Yuan; Guo, Xiaoqing; King, Sruthi T; Dorsam, Robert T; Atrakchi, Aisar H; McGovern, Timothy J; Davis-Bruno, Karen L; Keire, David A; Heflich, Robert H; Mei, Nan
细胞生物学
毒理研究
发表日期：2024
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