日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and "early aging" mice

接受辐射的受体小鼠在移植年轻、年老和“早衰”小鼠的骨髓后存活率

Ian Guest, Zoran Ilic, Heidi Scrable, Stewart Sell

P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion

P44 是 P53 的“长寿保证”异构体,可调节 tau 磷酸化,并以年龄依赖性方式激活

Mariana Pehar, Mi Hee Ko, Mi Li, Heidi Scrable, Luigi Puglielli

Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics

siRNA 药效学阳性读出小鼠模型的开发

Mark Stevenson, Robert Carlisle, Ben Davies, Chris Preece, Michelle Hammett, Wei-Li Liu, Kerry David Fisher, Amy Ryan, Heidi Scrable, Leonard William Seymour

Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice

Δ40 同工型 p53 控制小鼠 β 细胞增殖和葡萄糖稳态

Charlotte Hinault, Dan Kawamori, Chong Wee Liew, Bernhard Maier, Jiang Hu, Susanna R Keller, Raghavendra G Mirmira, Heidi Scrable, Rohit N Kulkarni

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

小鼠中 p53:p44 长寿保证活性改变导致记忆丧失、神经退化和过早死亡

Mariana Pehar, Kenneth J O'Riordan, Melissa Burns-Cusato, Matthew E Andrzejewski, Carlos Gil del Alcazar, Corinna Burger, Heidi Scrable, Luigi Puglielli

Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53

成年哺乳动物大脑神经前体的再生能力受 p53 的控制

Silvia Medrano, Melissa Burns-Cusato, Marybless B Atienza, Donya Rahimi, Heidi Scrable

Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R

Egr-1 和 Hipk2 是 IGF1-R 下游的 TrkA 到 p75(NTR) 转换所必需的。

Hui Li, Claudio Costantini, Heidi Scrable, Richard Weindruch, Luigi Puglielli

Phosphorylation regulates SIRT1 function

磷酸化调节 SIRT1 功能

Tsutomu Sasaki, Bernhard Maier, Katarzyna D Koclega, Maksymilian Chruszcz, Wendy Gluba, P Todd Stukenberg, Wladek Minor, Heidi Scrable

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

衰老通路控制 TrkA 到 p75NTR 受体的转换和淀粉样β肽的生成

Claudio Costantini, Heidi Scrable, Luigi Puglielli

Modulation of mammalian life span by the short isoform of p53

p53 短亚型对哺乳动物寿命的调节

Bernhard Maier, Wendy Gluba, Brian Bernier, Terry Turner, Khalid Mohammad, Theresa Guise, Ann Sutherland, Michael Thorner, Heidi Scrable