文献库，生知库 | 链接生命科学的每一步

日期影响因子

Harnessing Membrane-Active Peptides for Selective Cancer Targeting: Phosphatidylserine Recognition by Tilapia Piscidin 4

利用膜活性肽进行选择性癌症靶向：罗非鱼Piscidin 4对磷脂酰丝氨酸的识别

影响因子:8.7

doi:10.1021/jacsau.5c01524

Makambi, Wright K; De, Soumita; Li, Dandan; Mondal, Kinjal; Mitchell, Megan E; Kaur, Navleen; Watkins, Erik; Heinrich, Frank; Hoogerheide, David P; Klauda, Jeffery B; Rudloff, Udo; Cotten, Myriam L; Mihailescu, Mihaela

发表日期：2026

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An active allosteric mechanism in ASAP1-mediated Arf1 GTP hydrolysis redefines PH domain function

ASAP1介导的Arf1 GTP水解中的活性变构机制重新定义了PH结构域的功能

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-63764-w

Soubias, Olivier; Foley, Samuel L; Jian, Xiaoying; Jackson, Rebekah A; Zhang, Yue; Rosenberg, Eric M Jr; Hu, Benjamin J; Li, Jess; Heinrich, Frank; Johnson, Margaret E; Sodt, Alexander J; Randazzo, Paul A; Byrd, R Andrew

发表日期：2025

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Cyclization of Two Antimicrobial Peptides Improves Their Activity

两种抗菌肽的环化可提高其活性。

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c11466

Mitra, Saheli; Chen, Mei-Tung; Stedman, Francisca; Hernandez, Jedidiah; Kumble, Grace; Kang, Xi; Zhang, Churan; Tang, Grace; Reed, Iris; Daugherty, Ian Q; Liu, Wanqing; Klucznik, Kevin Raphael; Ocloo, Jeremy L; Li, Alexander Anzhi; Klousnitzer, Jessie; Heinrich, Frank; Deslouches, Berthony; Tristram-Nagle, Stephanie

发表日期：2025

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Poly-Arginine Tails and Helical Segments of Natural Antimicrobial Peptides Display Concerted Action at Membranes for Enhanced Antimicrobial Effects.

天然抗菌肽的聚精氨酸尾部和螺旋片段在细胞膜上协同作用，增强抗菌效果

期刊:ACS Bio & Med Chem Au

影响因子:4.3

doi:10.1021/acsbiomedchemau.5c00084

Kaur Navleen, Mondal Kinjal, Mitchell Megan E, Padi Sarala, Klauda Jeffery B, Cardone Antonio, Heinrich Frank, Harris Christina R, Giles David K, Rooney Mary T, Watkins Erik B, Cotten Myriam L, Hoogerheide David P, Mihailescu Mihaela

细胞生物学

发表日期：2025

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AI-driven antimicrobial peptide characterization unveils novel motifs for drug design

人工智能驱动的抗菌肽表征揭示了药物设计的新基序

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-30419-1

Padi, Sarala; Mondal, Kinjal; Hoogerheide, David P; Heinrich, Frank; Mihailescu, Mihaela; Klauda, Jeffery B; Cardone, Antonio

发表日期：2025

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The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism

ArfGAP ASAP1 中的 PH 结构域通过一种前所未有的变构机制驱动催化活化。

doi:10.21203/rs.3.rs-5462793/v1

Soubias, Olivier; Foley, Samuel L; Jian, Xiaoying; Jackson, Rebekah A; Zhang, Yue; Rosenberg, Eric M Jr; Li, Jess; Heinrich, Frank; Johnson, Margaret E; Sodt, Alexander J; Randazzo, Paul A; Byrd, R Andrew

发表日期：2025

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Redefining PH Domain Function: An Active Allosteric Mechanism in ASAP1-Mediated Arf1 GTP Hydrolysis

重新定义PH结构域功能：ASAP1介导的Arf1 GTP水解中的活性变构机制

doi:10.21203/rs.3.rs-6702895/v1

Randazzo, Paul; Soubias, Olivier; Foley, Samuel; Jian, Xiaoying; Jackson, Rebekah; Zhang, Yue; Rosenberg, Eric; Li, Jess; Heinrich, Frank; Johnson, Margaret; Sodt, Alexander; Byrd, R Andrew; Hu, Benjamin

发表日期：2025

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Correction to "Lung SPLUNC1 Peptide Derivatives in the Lipid Membrane Headgroup Kill Gram-Negative Planktonic and Biofilm Bacteria"

更正“肺SPLUNC1肽衍生物在脂质膜头部基团中杀死革兰氏阴性浮游细菌和生物膜细菌”

期刊:Biomacromolecules

影响因子:5.4

doi:10.1021/acs.biomac.4c00501

Jakkampudi, Tanvi; Lin, Qiao; Mitra, Saheli; Vijai, Aishwarya; Qin, Weiheng; Kang, Ann; Chen, Jespar; Ryan, Emma; Wang, Runxuan; Gong, Yuqi; Heinrich, Frank; Song, Junming; Di, Yuan-Pu Peter; Tristram-Nagle, Stephanie

发表日期：2024

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How Unnatural Amino Acids in Antimicrobial Peptides Change Interactions with Lipid Model Membranes

抗菌肽中的非天然氨基酸如何改变其与脂质模型膜的相互作用

期刊:Journal of Physical Chemistry B

影响因子:2.9

doi:10.1021/acs.jpcb.4c04152

Mitra, Saheli; Chen, Mei-Tung; Stedman, Francisca; Hernandez, Jedidiah; Kumble, Grace; Kang, Xi; Zhang, Churan; Tang, Grace; Daugherty, Ian; Liu, Wanqing; Ocloo, Jeremy; Klucznik, Kevin Raphael; Li, Alexander Anzhi; Heinrich, Frank; Deslouches, Berthony; Tristram-Nagle, Stephanie

发表日期：2024

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Novel non-helical antimicrobial peptides insert into and fuse lipid model membranes

新型非螺旋抗菌肽插入并融合脂质模型膜

期刊:Soft Matter

影响因子:2.8

doi:10.1039/d4sm00220b

Mitra, Saheli; Chandersekhar, Bhairavi; Li, Yunshu; Coopershlyak, Mark; Mahoney, Margot E; Evans, Brandt; Koenig, Rachel; Hall, Stephen C L; Klösgen, Beate; Heinrich, Frank; Deslouches, Berthony; Tristram-Nagle, Stephanie

发表日期：2024

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