日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Growth factors maintain intratumoral heterogeneity and drive therapeutic resistance in triple-negative breast cancer.

生长因子维持肿瘤内异质性,并导致三阴性乳腺癌的治疗耐药性。

Devlin Kaylyn L, Smith Rebecca, Bucher Elmar, Dane Mark, Bowman Chloe L, Carlson Eric J, Kilburn David, Sudar Damir, Feiler Heidi S, Heiser Laura M, Langer Ellen M, Korkola James E

Single-cell morphodynamical trajectories enable prediction of gene expression accompanying cell state change

单细胞形态动力学轨迹能够预测伴随细胞状态变化而发生的基因表达。

Copperman, Jeremy; Mclean, Ian C; Gross, Sean M; Singh, Jalim; Murthy, Vaibhav; Chang, Young Hwan; Davies, Alexander E; Zuckerman, Daniel M; Heiser, Laura M

Tumor-immune trajectory context connects static tissue architecture to clinical outcomes

肿瘤免疫轨迹背景将静态组织结构与临床结果联系起来

Cramer, Eric M; Heiland, Randy; da Rocha, Heber Lima; Bergman, Daniel R; Gray, Joe W; Mills, Gordon B; Fertig, Elana J; Macklin, Paul; Heiser, Laura M; Chang, Young Hwan

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

人类可理解的语法对多细胞系统生物学模型进行编码,以实现虚拟细胞实验室的普及化。

Johnson, Jeanette A I; Bergman, Daniel R; Rocha, Heber L; Zhou, David L; Cramer, Eric; Mclean, Ian C; Dance, Yoseph W; Booth, Max; Nicholas, Zachary; Lopez-Vidal, Tamara; Deshpande, Atul; Heiland, Randy; Bucher, Elmar; Shojaeian, Fatemeh; Dunworth, Matthew; Forjaz, André; Getz, Michael; Godet, Inês; Kurtoglu, Furkan; Lyman, Melissa; Metzcar, John; Mitchell, Jacob T; Raddatz, Andrew; Solorzano, Jacobo; Sundus, Aneequa; Wang, Yafei; DeNardo, David G; Ewald, Andrew J; Gilkes, Daniele M; Kagohara, Luciane T; Kiemen, Ashley L; Thompson, Elizabeth D; Wirtz, Denis; Wood, Laura D; Wu, Pei-Hsun; Zaidi, Neeha; Zheng, Lei; Zimmerman, Jacquelyn W; Phillip, Jude M; Jaffee, Elizabeth M; Gray, Joe W; Coussens, Lisa M; Chang, Young Hwan; Heiser, Laura M; Stein-O'Brien, Genevieve L; Fertig, Elana J; Macklin, Paul

Axon targeting of transcriptionally distinct pioneer neurons is regulated by retinoic acid signaling

转录上不同的先锋神经元的轴突靶向受视黄酸信号调控

Woodruff, Benjamin M; Miller, Lauren N; Calistri, Nicholas L; McVay, Jacqueline R; Heiser, Laura M; Nechiporuk, Alex V

Temporal reassignment and correspondence evaluation with quality control for time-course imaging of 3D cell culture.

3D细胞培养时间序列成像的时间重分配和对应性评估与质量控制。

Cramer Eric M, Lopez-Vidal Tamara, Johnson Jeanette, Wang Vania, Bergman Daniel R, Weeraratna Ashani, Burkhart Richard, Fertig Elana J, Zimmerman Jacquelyn W, Heiser Laura M, Chang Young Hwan

TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms

三阴性乳腺癌对紫杉醇的反应表型与干扰素反应相似,这揭示了细胞周期相关的耐药机制。

Calistri, Nicholas L; Liby, Tiera A; Hu, Zhi; Zhang, Hongmei; Dane, Mark A; Gross, Sean M; Heiser, Laura M

Neoplastic immune mimicry potentiates breast tumor progression

肿瘤免疫拟态促进乳腺肿瘤进展

Berens, Eric B; Khou, Sokchea; Huang, Elaine; Hoffman, Amber; Johnson, Briana; Kirchberger, Nell; Sivagnanam, Shamilene; Calistri, Nicholas L; Derrick, Daniel; Liby, Tiera A; McLean, Ian C; Alanizi, Aryn A; Ozmen, Furkan; Ozmen, Tugba Y; Mills, Gordon B; Hwang, E Shelley; Schedin, Pepper J; Gonzalez, Hugo; Werb, Zena; Heiser, Laura M; Coussens, Lisa M

Automated Quality Control of Time-Course Imaging from 3D in vitro cultures

三维体外培养时间序列成像的自动化质量控制

Cramer, Eric; Lopez-Vidal, Tamara; Johnson, Jeanette; Wang, Vania; Bergman, Daniel; Weeraratna, Ashani; Burkhart, Richard; Fertig, Elana J; Zimmerman, Jacquelyn W; Heiser, Laura M; Chang, Young Hwan

Oncostatin M orchestrates collective epithelial migration via HIF1A activation.

抑癌素 M 通过 HIF1A 激活来协调上皮细胞的集体迁移

McLean Ian C, Gross Sean M, Liby Tiera A, Dane Mark A, Derrick Daniel S, Heiser Laura M