日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PCI-DB: a novel primary tissue immunopeptidome database to guide next-generation peptide-based immunotherapy development

PCI-DB：一种新型的原发组织免疫肽组数据库，旨在指导下一代基于肽的免疫疗法的开发

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-011366
Lemke, Steffen; Dubbelaar, Marissa L; Zimmermann, Patrick; Bauer, Jens; Nelde, Annika; Hoenisch Gravel, Naomi; Scheid, Jonas; Wacker, Marcel; Jung, Susanne; Dengler, Anna; Maringer, Yacine; Rammensee, Hans-Georg; Gouttefangeas, Cecile; Fillinger, Sven; Bilich, Tatjana; Heitmann, Jonas S; Nahnsen, Sven; Walz, Juliane S
免疫/内分泌
发表日期：2025
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CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia

靶向CLEC12A的免疫细胞因子，具有靶细胞限制性IL-15活性，用于治疗急性髓系白血病

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1561823
Klimovich, Boris; Anton, Leonard; Jung, Jinwon; Lim, Yangmi; Lee, Bora; Won, Jonghwa; Zekri, Latifa; Chashchina, Anna; Pflügler, Martin; Heitmann, Jonas S; Jung, Gundram; Salih, Helmut R
白血病
细胞生物学
IL-15
免疫/内分泌
发表日期：2025
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B7-H3: a consistent marker in metastatic colorectal cancer with potential for targeted treatment

B7-H3：转移性结直肠癌中一种具有靶向治疗潜力的稳定标志物

期刊:Pathology & Oncology Research
影响因子:2.3
doi:10.3389/pore.2025.1612186
Ott, Julia M; Gassenmaier, Verena; Bitzer, Michael; Schürch, Christian M; Heitmann, Jonas S; Hagelstein, Ilona
肿瘤
肠癌
肿瘤免疫
发表日期：2025
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Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody

利用Fc优化CD276（B7-H3）抗体诱导NK细胞对急性髓系白血病的反应性

期刊:Blood Cancer Journal
影响因子:11.6
doi:10.1038/s41408-024-01050-6
Stefańczyk, Sylwia A; Hagelstein, Ilona; Lutz, Martina S; Müller, Stefanie; Holzmayer, Samuel J; Jarjour, Grace; Zekri, Latifa; Heitmann, Jonas S; Salih, Helmut R; Märklin, Melanie
CD276
白血病
CD27
细胞生物学
CD2
发表日期：2024
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Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients

基于仓库的、免疫肽组指导的个性化肽疫苗设计在慢性淋巴细胞白血病患者的临床试验评估中显示出可行性。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2024.1482715
Heitmann, Jonas S; Jung, Susanne; Wacker, Marcel; Maringer, Yacine; Nelde, Annika; Bauer, Jens; Denk, Monika; Hoenisch-Gravel, Naomi; Richter, Marion; Oezbek, Melek T; Dubbelaar, Marissa L; Bilich, Tatjana; Pumptow, Marina; Martus, Peter; Illerhaus, Gerald; Denzlinger, Claudio; Steinbach, Francesca; Aulitzky, Walter-Erich; Müller, Martin R; Dörfel, Daniela; Rammensee, Hans-Georg; Salih, Helmut R; Walz, Juliane S
白血病
细胞生物学
免疫/内分泌
发表日期：2024
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Protocol of a first-in-human clinical trial to evaluate the safety, tolerability, and preliminary efficacy of the bispecific CD276xCD3 antibody CC-3 in patients with colorectal cancer (CoRe_CC-3)

首次人体临床试验方案，旨在评估双特异性 CD276xCD3 抗体 CC-3 在结直肠癌患者中的安全性、耐受性和初步疗效 (CoRe_CC-3)

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2024.1351901
Jung, Susanne; Schlenk, Richard F; Hackenbruch, Christopher; Roldan Pinzon, Sandra S L; Bitzer, Michael; Pflügler, Martin; Walz, Juliane S; Jung, Gundram; Heitmann, Jonas S; Salih, Helmut R
肿瘤
肠癌
CD276
肿瘤免疫
CD3
CD27
CD2
发表日期：2024
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FusionVAC22_01: a phase I clinical trial evaluating a DNAJB1-PRKACA fusion transcript-based peptide vaccine combined with immune checkpoint inhibition for fibrolamellar hepatocellular carcinoma and other tumor entities carrying the oncogenic driver fusion

FusionVAC22_01：一项 I 期临床试验，评估基于 DNAJB1-PRKACA 融合转录本的肽疫苗联合免疫检查点抑制剂治疗纤维板层型肝细胞癌和其他携带致癌驱动融合基因的肿瘤的疗效。

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2024.1367450
Hackenbruch, Christopher; Bauer, Jens; Heitmann, Jonas S; Maringer, Yacine; Nelde, Annika; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Federmann, Birgit; Jung, Susanne; Martus, Peter; Malek, Nisar P; Nikolaou, Konstantin; Salih, Helmut R; Bitzer, Michael; Walz, Juliane S
细胞生物学
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2024
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iVAC-XS15-CLL01: personalized multi-peptide vaccination in combination with the TLR1/2 ligand XS15 in CLL patients undergoing BTK-inhibitor-based regimens

iVAC-XS15-CLL01：针对接受 BTK 抑制剂治疗方案的 CLL 患者，采用个性化多肽疫苗联合 TLR1/2 配体 XS15 进行治疗

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2024.1441625
Englisch, Alexander; Hayn, Clara; Jung, Susanne; Heitmann, Jonas S; Hackenbruch, Christopher; Maringer, Yacine; Nelde, Annika; Wacker, Marcel; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Martus, Peter; Salih, Helmut R; Walz, Juliane S
BTK
发表日期：2024
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AML-VAC-XS15-01: protocol of a first-in-human clinical trial to evaluate the safety, tolerability and preliminary efficacy of a multi-peptide vaccine based on leukemia stem cell antigens in acute myeloid leukemia patients

AML-VAC-XS15-01：一项首次人体临床试验方案，旨在评估基于白血病干细胞抗原的多肽疫苗在急性髓系白血病患者中的安全性、耐受性和初步疗效。

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2024.1458449
Jung, Susanne; Nelde, Annika; Maringer, Yacine; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Özbek, Melek; Martus, Peter; Hackenbruch, Christopher; Englisch, Alexander; Heitmann, Jonas S; Salih, Helmut R; Walz, Juliane S
白血病
细胞生物学
发育与干细胞
干细胞
发表日期：2024
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Phase I study evaluating the Fc-optimized FLT3 antibody FLYSYN in AML patients with measurable residual disease

一项评估Fc优化FLT3抗体FLYSYN在伴有可测量残留病灶的急性髓系白血病患者中疗效的I期研究

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-023-01490-w
Heitmann, Jonas S; Schlenk, Richard F; Dörfel, Daniela; Kayser, Sabine; Döhner, Konstanze; Heuser, Michael; Thol, Felicitas; Kapp-Schwoerer, Silke; Labrenz, Jannik; Edelmann, Dominic; Märklin, Melanie; Vogel, Wichard; Bethge, Wolfgang; Walz, Juliane S; Große-Hovest, Ludger; Steiner, Martin; Jung, Gundram; Salih, Helmut R
白血病
FLT3
发表日期：2023
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