Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283
6-氨基烟酸乙酯酰基磺酰胺作为P2Y12受体拮抗剂的先导优化。候选药物AZD1283的抗血栓作用和出血作用的分离
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm400820m
Peter Bach, Thomas Antonsson, Ruth Bylund, Jan-Arne Björkman, Krister Österlund, Fabrizio Giordanetto, J J J van Giezen, Søren M Andersen, Helen Zachrisson, Fredrik Zetterberg
