日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microbial dl-Peptidases Enable Predator Defense and Facilitate Structure Elucidation of Complex Natural Products

微生物 dl-肽酶能够防御捕食者并促进复杂天然产物的结构解析

Zhang, Shuaibing; Huang, Ying; Schlabach, Kevin; Tran, Mai Anh; Nachawati, Raed; Bader, Nicole; Komor, Anna J; Hertweck, Christian; Schindelin, Hermann; Lakemeyer, Markus; Hellmich, Ute A; Stallforth, Pierre

Quantifying Protein Homodimer Affinities and the Effect of Molecular Glues and Interface Residues Using Native Mass Spectrometry

利用天然质谱法定量分析蛋白质同源二聚体亲和力以及分子胶和界面残基的影响

Schulte, Jonathan; Schwegler, Eric; Hellmich, Ute A; Morgner, Nina

Profiling the TRPV4 ankyrin repeat domain interactome and its disruption by neuromuscular disease-causing mutations

分析TRPV4锚蛋白重复结构域相互作用组及其受神经肌肉疾病致病突变的影响

Loder, Alexis K; Kosmanopoulos, Gage P; Aisenberg, William H; Cox, Eric; Meeker, Alexis R; Blackshaw, Seth; Gaudet, Rachelle; Hellmich, Ute A; McCray, Brett A; Sumner, Charlotte J; Sullivan, Jeremy M

Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes

质子化的谷氨酸和天冬氨酸侧链可通过强而短的氢键识别生物大分子复合物中的磷酸二酯基团。

Neißner, Konstantin; Duchardt-Ferner, Elke; Wiedemann, Christoph; Kraus, Julian; Hellmich, Ute A; Wöhnert, Jens

Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter

IV型多药ABC转运蛋白中核苷酸和底物结合位点之间的双向通讯

Carrillo, Victor Hugo Pérez; Di Cesare, Margot; Rose-Sperling, Dania; Javed, Waqas; Neuweiler, Hannes; Marcoux, Julien; Orelle, Cédric; Jault, Jean-Michel; Hellmich, Ute A

Actifensin Evolution in the Human Oral Cavity over the Past 100,000 Years

过去10万年间人类口腔中放线菌素的演变

Herbst, Rosa; Ibrahim, Anan; Hübner, Alexander; Knüpfer, Uwe; Regestein, Lars; Wiedemann, Christoph; Hellmich, Ute A; Warinner, Christina; Stallforth, Pierre

Combined clinical, structural and cellular studies discriminate pathogenic and benign TRPV4 variants.

结合临床、结构和细胞研究,可以区分致病性和良性 TRPV4 变异体

Berth Sarah H, Vo Linh, Kwon Do Hoon, Grider Tiffany, Damayanti Yasmine S, Kosmanopoulos Gage, Fox Andrew, Lau Alexander R, Carr Patrice, Donohue Jack K, Hoke Maya, Thomas Simone, Karam Chafic, Fay Alex J, Meltzer Ethan, Crawford Thomas O, Gaudet Rachelle, Shy Michael E, Hellmich Ute A, Lee Seok-Yong, Sumner Charlotte J, McCray Brett A

Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors

致病细菌和原生动物巨噬细胞感染增强蛋白与氟化哌啶酸抑制剂结合的结构和动力学

Pérez Carrillo, Victor Hugo; Whittaker, Jacob J; Wiedemann, Christoph; Harder, Jean-Martin; Lohr, Theresa; Jamithireddy, Anil K; Dajka, Marina; Goretzki, Benedikt; Joseph, Benesh; Guskov, Albert; Harmer, Nicholas J; Holzgrabe, Ulrike; Hellmich, Ute A

AMPylation Regulates 5'-3' Exonuclease PLD3 Processing

AMP化调控5'-3'外切核酸酶PLD3的加工

Hoffmann, Laura; Eckl, Eva-Maria; Bérouti, Marleen; Pries, Michael; Koller, Aron; Guhl, Charlotte; Hellmich, Ute A; Hornung, Veit; Xiang, Wei; Jae, Lucas T; Kielkowski, Pavel

Strategic Acyl Carrier Protein Engineering Enables Functional Type II Polyketide Synthase Reconstitution In Vitro

策略性酰基载体蛋白工程实现体外功能性II型聚酮合酶的重组

Li, Kevin; Cho, Yae In; Tran, Mai Anh; Wiedemann, Christoph; Zhang, Shuaibing; Koweek, Rebecca S; Hoàng, Ngọc Khánh; Hamrick, Grayson S; Bowen, Margaret A; Kokona, Bashkim; Stallforth, Pierre; Beld, Joris; Hellmich, Ute A; Charkoudian, Louise K