日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic drug monitoring of daptomycin in a critically ill patient cohort

达托霉素在危重患者群体中的治疗药物监测

Hellwege, Rubi Stephani; Müller, Mattia; Erlebach, Rolf; Sazpinar, Onur; Buhlmann, Alix; Schuepbach, Reto A; David, Sascha; Hofmaenner, Daniel A

Multi-ancestry meta-analysis of keloids uncovers novel susceptibility loci in diverse populations

一项针对瘢痕疙瘩的多民族荟萃分析揭示了不同人群中新的易感基因位点

Greene, Catherine A; Hampton, Gabrielle; Jaworski, James; Shuey, Megan M; Khan, Atlas; Luo, Yuan; Jarvik, Gail P; Namjou-Khales, Bahram; Edwards, Todd L; Velez Edwards, Digna R; Hellwege, Jacklyn N

Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups

全基因组荟萃分析在多个祖先群体内部和之间发现了子宫肌瘤的新风险位点

Kim, Jeewoo; Williams, Ariel; Noh, Hannah; Jasper, Elizabeth A; Jones, Sarah H; Jaworski, James A; Shuey, Megan M; Ruiz-Narváez, Edward A; Wise, Lauren A; Palmer, Julie R; Connolly, John; Keaton, Jacob M; Denny, Joshua C; Khan, Atlas; Abbass, Mohammad A; Rasmussen-Torvik, Laura J; Kottyan, Leah C; Madhivanan, Purnima; Krupp, Karl; Wei, Wei-Qi; Edwards, Todd L; Velez Edwards, Digna R; Hellwege, Jacklyn N

Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction

基于基因组学的药物重定位策略确定了两个可用于预防与代谢功能障碍相关的肝脏疾病的治疗靶点

Seagle, Hannah M; Akerele, Alexis T; DeCorte, Joseph A; Hellwege, Jacklyn N; Breeyear, Joseph H; Kim, Jeewoo; Levin, Michael G; Khodursky, Samuel; Bress, Adam; Lee, Kyung Min; Meiler, Jens; Gill, Dipender; Lee, Jennifer S; Heberer, Kent; Miller, Donald R; Reaven, Peter D; Chang, Kyong-Mi; Lynch, Julie A; Khankari, Nikhil K; Shuey, Megan M; Edwards, Todd L; Vujkovic, Marijana

Genetic analysis in African ancestry populations reveals genetic contributors to lung cancer susceptibility

对非洲裔人群的基因分析揭示了肺癌易感性的遗传因素

Betti, Michael J; Jaworski, James; Zhao, Shilin; Rao, J Sunil; Ryan, Bríd M; Schwartz, Ann G; Lusk, Christine M; McCoy, Lucie; Wiencke, John K; Bruce, Marino A; Chanock, Stephen; Gamazon, Eric R; Hellwege, Jacklyn N; Aldrich, Melinda C

Genetically Predicted Gene Expression Effects on Changes in Red Blood Cell and Plasma Polyunsaturated Fatty Acids

基因预测的基因表达对红细胞和血浆多不饱和脂肪酸变化的影响

Khankari, Nikhil K; Su, Timothy; Cai, Qiuyin; Liu, Lili; Jasper, Elizabeth A; Hellwege, Jacklyn N; Murff, Harvey J; Shrubsole, Martha J; Long, Jirong; Edwards, Todd L; Zheng, Wei

Genomics-Informed Drug Repurposing Strategy Identifies Novel Therapeutic Targets for Metabolic Dysfunction-Associated Steatotic Liver Disease

基于基因组学的药物重定位策略揭示了代谢功能障碍相关脂肪肝疾病的新治疗靶点

Seagle, Hannah M; Akerele, Alexis T; DeCorte, Joseph A; Hellwege, Jacklyn N; Breeyear, Joseph H; Kim, Jeewoo; Levin, Michael; Khodurksy, Samuel; Bress, Adam; Lee, Kyung; Meiler, Jens; Gill, Dipender; Lee, Jennifer S; Heberer, Kent; Miller, Donald R; Reaven, Peter; Chang, Kyong-Mi; Lynch, Julie A; Khankari, Nikhil K; Shuey, Megan M; Edwards, Todd L; Vujkovic, Marijana

Constructing a multi-ancestry polygenic risk score for uterine fibroids using publicly available data highlights need for inclusive genetic research

利用公开数据构建子宫肌瘤的多祖源多基因风险评分,凸显了开展包容性遗传研究的必要性。

Winters, Jessica L G; Piekos, Jacqueline A; Hellwege, Jacklyn N; Dikilitas, Ozan; Kullo, Iftikhar J; Schaid, Daniel J; Edwards, Todd L; Velez Edwards, Digna R

A phenome-wide association study of uterine fibroids reveals a marked burden of comorbidities

一项针对子宫肌瘤的全表型关联研究揭示了其显著的合并症负担

Jasper, Elizabeth A; Mautz, Brian S; Hellwege, Jacklyn N; Piekos, Jacqueline A; Jones, Sarah H; Zhang, Yanfei; Torstenson, Eric S; Pendergrass, Sarah A; Lee, Ming Ta Michael; Edwards, Todd L; Velez Edwards, Digna R

Uterine fibroids show evidence of shared genetic architecture with blood pressure traits

子宫肌瘤与血压特征显示出共同的遗传结构。

Akerele, Alexis T; Piekos, Jacqueline A; Kim, Jeewoo; Khankari, Nikhil K; Hellwege, Jacklyn N; Edwards, Todd L; Velez Edwards, Digna R