日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High Pressure Phase-Transformation Induced Texture Evolution and Strengthening in Zirconium Metal: Experiment and Modeling

高压相变诱导锆金属织构演变及强化:实验与建模

Yu, Xiaohui; Zhang, Ruifeng; Weldon, David; Vogel, Sven C; Zhang, Jianzhong; Brown, Donald W; Wang, Yanbin; Reiche, Helmut M; Wang, Shanmin; Du, Shiyu; Jin, Changqing; Zhao, Yusheng

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction

乙肝和丙肝中功能失调的 CD8+ T 细胞的特点是缺乏抗原特异性 T-bet 诱导

Peter D Kurktschiev, Bijan Raziorrouh, Winfried Schraut, Markus Backmund, Martin Wächtler, Clemens-Martin Wendtner, Bertram Bengsch, Robert Thimme, Gerald Denk, Reinhart Zachoval, Andrea Dick, Michael Spannagl, Jürgen Haas, Helmut M Diepolder, Maria-Christina Jung, Norbert H Gruener

Encapsulated cells expressing a chemotherapeutic activating enzyme allow the targeting of subtoxic chemotherapy and are safe and efficacious: data from two clinical trials in pancreatic cancer

表达化疗激活酶的封装细胞能够实现亚毒性化疗的靶向治疗,且安全有效:来自两项胰腺癌临床试验的数据

Löhr, J Matthias; Haas, Stephan L; Kröger, Jens C; Friess, Helmut M; Höft, Raimund; Goretzki, Peter E; Peschel, Christian; Schweigert, Markus; Salmons, Brian; Gunzburg, Walter H

Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules

HBV 特异性 CD4+ T 细胞的抑制表型以 PD-1 表达高但缺乏多种抑制分子的共调节为特征

Bijan Raziorrouh, Malte Heeg, Peter Kurktschiev, Winfried Schraut, Reinhart Zachoval, Clemens Wendtner, Martin Wächtler, Michael Spannagl, Gerald Denk, Axel Ulsenheimer, Bertram Bengsch, Hanspeter Pircher, Helmut M Diepolder, Norbert H Grüner, Maria-Christina Jung

Lack of variant specific CD8+ T-cell response against mutant and pre-existing variants leads to outgrowth of particular clones in acute hepatitis C

缺乏针对突变型和既有变异株的特异性CD8+ T细胞反应会导致急性丙型肝炎中特定克隆的过度增殖。

Ulsenheimer, Axel; Paranhos-Baccalà, Gláucia; Komurian-Pradel, Florence; Raziorrouh, Bijan; Kurktschiev, Peter; Diepolder, Helmut M; Zachoval, Reinhart; Spannagl, Michael; Jung, Maria-Christina; Gruener, Norbert H

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity

急性期和早期丙型肝炎病毒感染中病毒进化的受限模式限制了病毒的可塑性。

Pfafferott, Katja; Gaudieri, Silvana; Ulsenheimer, Axel; James, Ian; Heeg, Malte; Nolan, David; John, Mina; Rauch, Andri; Mallal, Simon; Lucas, Andrew; Klenerman, Paul; Diepolder, Helmut M; Lucas, Michaela

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.

对λ干扰素IL-28A和IL-29的转录组及其抗丙型肝炎病毒的抗病毒特性进行比较分析

Diegelmann Julia, Beigel Florian, Zitzmann Kathrin, Kaul Artur, Göke Burkhard, Auernhammer Christoph J, Bartenschlager Ralf, Diepolder Helmut M, Brand Stephan

Microwave multicomponent synthesis

微波多组分合成

Hügel, Helmut M

Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells

清道夫受体 B 类是人类树突状细胞吸收和交叉呈递丙型肝炎病毒所必需的

Heidi Barth, Eva K Schnober, Christoph Neumann-Haefelin, Christine Thumann, Mirjam B Zeisel, Helmut M Diepolder, Zongyi Hu, T Jake Liang, Hubert E Blum, Robert Thimme, Mélanie Lambotin, Thomas F Baumert

The role of interleukin-22 in hepatitis C virus infection

白细胞介素-22在丙型肝炎病毒感染中的作用

Julia Dambacher, Florian Beigel, Kathrin Zitzmann, Malte H J Heeg, Burkhard Göke, Helmut M Diepolder, Christoph J Auernhammer, Stephan Brand