日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans

分泌型卷曲相关蛋白3 (sFRP3) 调节小鼠和人类的抗抑郁反应

Jang, M-H; Kitabatake, Y; Kang, E; Jun, H; Pletnikov, M V; Christian, K M; Hen, R; Lucae, S; Binder, E B; Song, H; Ming, G-I

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

小鼠海马星形胶质细胞中BDNF的过表达可促进局部神经发生并产生类似抗焦虑的活性

Quesseveur, G; David, D J; Gaillard, M C; Pla, P; Wu, M V; Nguyen, H T; Nicolas, V; Auregan, G; David, I; Dranovsky, A; Hantraye, P; Hen, R; Gardier, A M; Déglon, N; Guiard, B P

Antidepressants recruit new neurons to improve stress response regulation

抗抑郁药通过募集新的神经元来改善应激反应调节。

Surget, A; Tanti, A; Leonardo, E D; Laugeray, A; Rainer, Q; Touma, C; Palme, R; Griebel, G; Ibarguen-Vargas, Y; Hen, R; Belzung, C

Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity.

血清素1B受体表达不足会导致与年龄相关的运动功能障碍、大脑分子衰老过早发生以及寿命缩短

Sibille E, Su J, Leman S, Le Guisquet A M, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng G C, Pezzone M, Hen R, Belzung C

Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice

血清素 (5-HT) 1B 受体的过度激活会破坏单胺氧化酶 A 和 5-HT 转运蛋白敲除小鼠的感觉图谱形成。

Salichon, N; Gaspar, P; Upton, A L; Picaud, S; Hanoun, N; Hamon, M; De Maeyer, E; Murphy, D L; Mossner, R; Lesch, K P; Hen, R; Seif, I

5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze

5-HT1B受体敲除小鼠表现出更强的探索行为和在莫里斯水迷宫中更强的空间记忆能力。

Malleret, G; Hen, R; Guillou, J L; Segu, L; Buhot, M C

Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice

5-HT1B受体在调节异相睡眠中的关键作用已在5-HT1B基因敲除小鼠中得到证实。

Boutrel, B; Franc, B; Hen, R; Hamon, M; Adrien, J

Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice

5-羟色胺1B受体敲除小鼠中,芬氟拉明诱导的厌食症消失,且下丘脑和中央杏仁核复合体中c-Fos的诱导减少。

Lucas, J J; Yamamoto, A; Scearce-Levie, K; Saudou, F; Hen, R

Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system

弗里德赖希共济失调基因座区域的基因编码一种推测的跨膜蛋白,该蛋白在神经系统中表达。

Duclos, F; Boschert, U; Sirugo, G; Mandel, J L; Hen, R; Koenig, M

Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers

小鼠5HT1B血清素受体:克隆、功能表达及在运动控制中心的定位

Maroteaux, L; Saudou, F; Amlaiky, N; Boschert, U; Plassat, J L; Hen, R