日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epidermal Stem Cell-Derived Extracellular Vesicles Induce Fibroblasts Mesenchymal-Epidermal Transition to Alleviate Hypertrophic Scar Formation via miR-200s Inhibition of ZEB1 and 2

表皮干细胞来源的细胞外囊泡通过miR-200抑制ZEB1和ZEB2诱导成纤维细胞间质-表皮转化,从而减轻肥厚性瘢痕形成。

Miao Zhen ,Juntao Xie ,Rui Yang ,Lijuan Liu ,Hengdeng Liu ,Xuefeng He ,Suyue Gao ,Junyou Zhu ,Jingting Li ,Bin Shu ,Peng Wang

Epidermal stem cell derived exosomes-induced dedifferentiation of myofibroblasts inhibits scarring via the miR-203a-3p/PIK3CA axis

表皮干细胞来源的外泌体诱导的肌成纤维细胞去分化通过 miR-203a-3p/PIK3CA 轴抑制瘢痕形成

Shixin Zhao #, Haoran Kong #, Dahu Qi #, Yushuang Qiao #, Yu Li, Zhiming Cao, Hanwen Wang, Xuefeng He, Hengdeng Liu, Hao Yang, Suyue Gao, Tao Liu, Julin Xie

Nanocomposite-loaded hybrid microneedles reshape dermal microenvironment through senolytic delivery and collagen XVII-mediated barrier repair.

纳米复合材料负载的混合微针通过衰老细胞清除和胶原蛋白 XVII 介导的屏障修复来重塑真皮微环境。

Yang Fan, Xiong Yahui, Chen Shuying, Bie Fan, Li Zhanpeng, Liu Hengdeng, Liu Lijuan, Zhang Zhaoqiang, Chen Lei

From inflammation to healing: the crucial role of GPR91 activation and SDH inhibition in chronic diabetic wound recovery.

从炎症到愈合:GPR91 激活和 SDH 抑制在慢性糖尿病伤口愈合中的关键作用

Liu Hengdeng, Zhao Shixin, Wang Hanwen, He Xuefeng, Gao Suyue, Su Minmin, Zhen Miao, Chen Shuying, Chen Lei, Xie Julin

Single-cell RNA sequencing reveals the impaired epidermal differentiation and pathological microenvironment in diabetic foot ulcer

单细胞 RNA 测序揭示糖尿病足部溃疡表皮分化受损和病理微环境

Yiling Liu, Peng Wang, Jingting Li, Lei Chen, Bin Shu, Hanwen Wang, Hengdeng Liu, Shixin Zhao, Junli Zhou, Xiaodong Chen, Julin Xie

Paquinimod-hydrogel hybrid microneedle array patch alleviates hypertrophic scar via inhibiting M1 polarization.

Paquinimod-水凝胶混合微针阵列贴片通过抑制M1极化来缓解肥厚性瘢痕。

Zhang Zihui, Wang Peng, Liu Hengdeng, Wang Hanwen, Zhen Miao, He Xuefeng, Gao Suyue, Xie Juntao, Xie Julin

Approaches to scarless burn wound healing: application of 3D printed skin substitutes with dual properties of anti-infection and balancing wound hydration levels

无瘢痕烧伤伤口愈合方法:应用具有抗感染和平衡伤口水分水平双重特性的 3D 打印皮肤替代品

Shuying Chen, Yahui Xiong, Fan Yang, Yanke Hu, Jinghao Feng, Fei Zhou, Zhonghua Liu, Hengdeng Liu, Xiaogang Liu, Jingling Zhao, Zhaoqiang Zhang, Lei Chen

Inhibition of phosphatidylinositol 3-kinase catalytic subunit alpha by miR-203a-3p reduces hypertrophic scar formation via phosphatidylinositol 3-kinase/AKT/mTOR signaling pathway

miR-203a-3p通过抑制磷脂酰肌醇3-激酶催化亚基α,经由磷脂酰肌醇3-激酶/AKT/mTOR信号通路减少肥厚性瘢痕的形成。

Zhao, Shixin; Liu, Hengdeng; Wang, Hanwen; He, Xuefeng; Tang, Jinming; Qi, Shaohai; Yang, Ronghua; Xie, Julin

ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m6A-dependent manner

ALKBH5 通过介导 ABCA1 去甲基化并以 m6A 依赖的方式调节自噬,促进皮肤黑色素瘤的进展

Hanwen Wang, Shixin Zhao, Hengdeng Liu, Yiling Liu, Zihui Zhang, Ziheng Zhou, Peng Wang, Shaohai Qi, Julin Xie

System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma

基于细胞焦亡相关基因的系统分析确定 GSDMD 是皮肤黑色素瘤的新治疗靶点

Shixin Zhao #, Yongkang Zhu #, Hengdeng Liu #, Xuefeng He, Julin Xie