日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Highly effective combination of BRG1/BRM inhibitor with BET inhibitor or decitabine for high-risk MECOM-rearranged AML

BRG1/BRM抑制剂联合BET抑制剂或地西他滨治疗高危MECOM重排急性髓系白血病疗效显著。

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70289
Fiskus, Warren; Mill, Christopher P; Piel, Jessica; Collins, Mike; Hentemann, Murphy; Cuglievan, Branko; Birdwell, Christine E; Das, Kaberi; Davis, John A; Hou, Hanxi; Jain, Antrix; Malovannaya, Anna; Flores, Lauren B; Kadia, Tapan M; Daver, Naval; Sasaki, Koji; Takahashi, Koichi; Hammond, Danielle; Wang, Jian; Loghavi, Sanam; Su, Xiaoping; DiNardo, Courtney D; Delwel, Ruud; Bhalla, Kapil N
白血病
BRM
发表日期：2026
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Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations

BRG1/BRM与FLT3抑制剂联合治疗对FLT3突变型AML细胞具有优异的临床前疗效

期刊:Blood Cancer Journal
影响因子:11.6
doi:10.1038/s41408-025-01251-7
Fiskus, Warren; Mill, Christopher P; Piel, Jessica; Collins, Mike; Hentemann, Murphy; Cuglievan, Branko; Birdwell, Christine E; Das, Kaberi; Hou, Hanxi; Davis, John A; Jain, Antrix; Malovannaya, Anna; Kadia, Tapan M; Daver, Naval; Sasaki, Koji; Takahashi, Koichi; Hammond, Danielle; Reville, Patrick K; Flores, Lauren B; Loghavi, Sanam; Su, Xiaoping; DiNardo, Courtney D; Bhalla, Kapil N
细胞生物学
BRM
FLT3
发表日期：2025
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor

BRG1/BRM抑制剂靶向AML干细胞，与BET或menin抑制剂联合使用时，在临床前疗效显著优于其他抑制剂。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023022832
Fiskus, Warren; Piel, Jessica; Collins, Mike; Hentemann, Murphy; Cuglievan, Branko; Mill, Christopher P; Birdwell, Christine E; Das, Kaberi; Davis, John A; Hou, Hanxi; Jain, Antrix; Malovannaya, Anna; Kadia, Tapan M; Daver, Naval; Sasaki, Koji; Takahashi, Koichi; Hammond, Danielle; Reville, Patrick K; Wang, Jian; Loghavi, Sanam; Sen, Rwik; Ruan, Xinjia; Su, Xiaoping; Flores, Lauren B; DiNardo, Courtney D; Bhalla, Kapil N
细胞生物学
发育与干细胞
BRM
干细胞
发表日期：2024
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Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)

新型 2,3-二氢咪唑并[1,2-c]喹唑啉 PI3K 抑制剂的发现和构效关系研究：Copanlisib (BAY 80-6946) 的鉴定

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.201600148
Scott, William J; Hentemann, Martin F; Rowley, R Bruce; Bull, Cathy O; Jenkins, Susan; Bullion, Ann M; Johnson, Jeffrey; Redman, Anikó; Robbins, Arthur H; Esler, William; Fracasso, R Paul; Garrison, Timothy; Hamilton, Mark; Michels, Martin; Wood, Jill E; Wilkie, Dean P; Xiao, Hong; Levy, Joan; Stasik, Enrico; Liu, Ningshu; Schaefer, Martina; Brands, Michael; Lefranc, Julien
发表日期：2016
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Genetic analysis of common diseases: Applications to predictive factors in coronary disease

常见疾病的基因分析：在冠心病预测因素中的应用

期刊:American Journal of Human Genetics
影响因子:8.1
doi:
Eiben, B; Bartels, I; Bähr-Porsch, S; Borgmann, S; Gatz, G; Gellert, G; Goebel, R; Hammans, W; Hentemann, M; Osmers, R; Wilson, Miriam G; Rahbar, Samuel; Siervogel, R M
心血管
冠心病
发表日期：1981
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