日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Analgesia and peripheral c-fiber modulation by selective Na v 1.8 inhibition in rhesus.

选择性抑制 Na v 1.8 对恒河猴镇痛和外周 C 纤维调节的影响

Vardigan Joshua D, Pall Parul S, McDevitt Dillon S, Huang ChienJung, Clements Michelle K, Li Yuxing, Kraus Richard L, Breslin Michael J, Bungard Christopher J, Nemenov Mikhail I, Klukinov Mikhail, Burgey Chritopher S, Layton Mark E, Stachel Shawn J, Lange Henry S, Savitz Alan T, Santarelli Vincent P, Henze Darrell A, Uslaner Jason M

Humanized Na(V)1.8 rats overcome cross-species potency shifts in developing novel Na(V)1.8 inhibitors.

人源化 Na(V)1.8 大鼠克服了开发新型 Na(V)1.8 抑制剂时跨物种效力变化的问题

McDevitt Dillon S, Vardigan Joshua D, Zhou Xiaoping, Rosahl Thomas W, Zhou Heather, Price Eric A, Clements Michelle K, Li Yuxing, Varghese Nissi, Krasowska-Zoladek Alicja, Stachel Shawn J, Breslin Michael J, Burgey Christopher S, Kraus Richard L, Pall Parul S, Henze Darrell A, Santarelli Vincent P

Multi-omics profiles of chronic low back pain and fibromyalgia-Study protocol

慢性腰痛和纤维肌痛的多组学分析——研究方案

Curatolo, Michele; Chiu, Abby P; Chia, Catherine; Ward, Ava; Khan, Savera; Johnston, Sandra K; Klein, Rebecca M; Henze, Darrell A; Zhu, Wentao; Raftery, Daniel

Spatial transcriptomic profiling of human paravertebral sympathetic chain ganglia reveals diabetes-induced neuroplasticity

人类椎旁交感神经链神经节的空间转录组分析揭示了糖尿病诱导的神经可塑性

Mancilla Moreno, Marisol; Patel, Pooja J; Goss, Kree; Mian, Subhaan M; Nakisli, Sera; Inturi, Nikhil; Shiers, Stephanie I; Horton, Peter; Cervantes, Anna; Funk, Geoffrey; Khan, Tariq; Vines, Erin; Klein, Rebecca M; Henze, Darrell A; Tavares-Ferreira, Diana; Price, Theodore J; Yousuf, Muhammad Saad

Multi-Omics Profiles of Chronic Low Back Pain and Fibromyalgia - Study Protocol

慢性腰痛和纤维肌痛的多组学分析——研究方案

Curatolo, Michele; Chiu, Abby P; Chia, Catherine; Ward, Ava; Johnston, Sandra K; Klein, Rebecca M; Henze, Darrell A; Zhu, Wentao; Raftery, Daniel

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

呼吸衰竭与膈神经中NaV1.6抑制有关

Klein, Rebecca M; Layton, Mark E; Regan, Hillary; Regan, Christopher P; Li, Yuxing; Filzen, Tracey; Cato, Matt; Clements, Michelle K; Wang, Jixin; Sanoja, Raul; Greshock, Thomas J; Roecker, Anthony J; Pero, Joseph E; Kim, Ron; Burgey, Christopher; John, Christopher T; Wang, Ying-Hong; Bhandari, Neetesh; Struyk, Arie; Kraus, Richard L; Henze, Darrell A; Houghton, Andrea K

Translational Pharmacokinetic-Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose

利用转化药代动力学-药效学模型研究NaV1.7抑制剂MK-2075在人体中的有效剂量

Ballard, Jeanine E; Pall, Parul S; Vardigan, Joshua; Zhao, Fuqiang; Holahan, Marie A; Zhou, Xiaoping; Jochnowitz, Nina; Kraus, Richard L; Klein, Rebecca M; Henze, Darrell A; Houghton, Andrea K; Burgey, Christopher S; Gibson, Christopher; Struyk, Arie

Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

对一种新型非人灵长类动物热反应性测量方法进行药理学验证,该方法可用于预测镇痛效果

Vardigan, Joshua D; Houghton, Andrea K; Lange, Henry S; Adarayan, Emily D; Pall, Parul S; Ballard, Jeanine E; Henze, Darrell A; Uslaner, Jason M

HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

HC-030031 是一种 TRPA1 选择性拮抗剂,可减轻炎症和神经病变引起的机械性痛觉过敏。

Eid, Samer R; Crown, Eric D; Moore, Eric L; Liang, Hongyu A; Choong, Kar-Chan; Dima, Shelley; Henze, Darrell A; Kane, Stefanie A; Urban, Mark O

Three-dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo

对活体记录并填充的CA3锥体细胞轴突树突进行三维重建

Wittner, Lucia; Henze, Darrell A; Záborszky, László; Buzsáki, György