日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD

非典型DAT缺乏综合征的小鼠模型揭示了与帕金森病和ADHD相关的多巴胺功能障碍

Herborg, Freja; Konrad, Lisa K; Jørgensen, Søren H; Lilja, Jamila H; Delignat-Lavaud, Benoît; Posselt, Leonie P; Pugh, Ciara F; Bach, Sofie A; Ratner, Cecilia F; Awadallah, Nora; Pino, Jose A; Berlin, Frida; Ejdrup, Aske L; Olesen, Mikkel V; Rickhag, Mattias; Holst, Birgitte; Aznar, Susana; Mayer, Felix P; Woldbye, David; Torres, Gonzalo; Trudeau, Louis-Eric; Gether, Ulrik

Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum

计算模型揭示了纹状体亚区特异性多巴胺动态的关键决定因素

Ejdrup, Aske; Dreyer, Jakob Kisbye; Lycas, Matthew D; Jørgensen, Søren H; Robbins, Trevor W; Dalley, Jeffrey; Herborg, Freja; Gether, Ulrik

Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs.

两亲性螺旋 8 与膜曲率的关联驱动 GPCR 的组成型内吞作用

Schmidt Jan Hendrik, Herlo Rasmus, Rombach Joscha, Larsen Andreas Haahr, Stoklund Mikkel, Perslev Mathias, Nielsen Tommas Theiss Ehler, Andersen Keenie Ayla, Herenbrink Carmen Klein, Lycas Matthew D, Ejdrup Aske Lykke, Christensen Nikolaj Riis, Christensen Jan P, Salman Mootaz, Herborg Freja, Gether Ulrik, Hauser Alexander Sebastian, Bassereau Patricia, Perrais David, Madsen Kenneth Lindegaard

Three-dimensional cell-cell interactions promote direct reprogramming of patient fibroblasts into functional and transplantable neurons.

三维细胞间相互作用促进患者成纤维细胞直接重编程为功能性可移植神经元

Kajtez Janko, Laurin Kerstin, Nilsson Fredrik, Bruzelius Andreas, Cepeda-Prado Efrain, Birtele Marcella, Barker Roger A, Herborg Freja, Rylander Ottosson Daniella, Storm Petter, Fiorenzano Alessandro, Habekost Mette, Parmar Malin

Parkinson's disease gene, Synaptojanin1, dysregulates the surface maintenance of the dopamine transporter

帕金森病基因 Synaptojanin1 会扰乱多巴胺转运蛋白的表面维持。

Saenz, Jacqueline; Khezerlou, Elnaz; Aggarwal, Meha; Shaikh, Amina; Ganti, Naga; Herborg, Freja; Pan, Ping-Yue

Amphetamine-induced reverse transport of dopamine does not require cytosolic Ca(2)

苯丙胺诱导的多巴胺逆向转运不需要胞质Ca(2)

Støier, Jonatan Fullerton; Konomi-Pilkati, Ainoa; Apuschkin, Mia; Herborg, Freja; Gether, Ulrik

Multimodal detection of dopamine by sniffer cells expressing genetically encoded fluorescent sensors.

利用表达基因编码荧光传感器的嗅探细胞进行多模态多巴胺检测

Klein Herenbrink Carmen, Støier Jonatan Fullerton, Reith William Dalseg, Dagra Abeer, Gregorek Miguel Alejandro Cuadrado, Cola Reto B, Patriarchi Tommaso, Li Yulong, Tian Lin, Gether Ulrik, Herborg Freja

Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes

与神经精神疾病相关的多巴胺转运蛋白基因变异表现出异质性分子表型

Herborg, Freja; Andreassen, Thorvald F; Berlin, Frida; Loland, Claus J; Gether, Ulrik