日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TGF-β/SMAD4/14-3-3σ/TFEB axis promotes mesenchymal-epithelial transition and inhibits autophagy in colorectal cancer

TGF-β/SMAD4/14-3-3σ/TFEB轴促进结直肠癌间质-上皮转化并抑制自噬

Chen, Xiaoyan; Winter, Markus; Rokavec, Matjaz; König, Janine; Hermeking, Heiko

RBM47-Induced Gasdermin A/GSDMA Mediates Mesenchymal-Epithelial Transition and Pyroptosis of Colorectal Cancer Cells

RBM47诱导的Gasdermin A/GSDMA介导结直肠癌细胞的间质-上皮转化和细胞焦亡

Du, Yuyun; Rokavec, Matjaz; Hermeking, Heiko

Myeloid Mir34a suppresses colitis-associated colon cancer: characterization of mediators by single-cell RNA sequencing

髓系 Mir34a 抑制结肠炎相关结肠癌:单细胞 RNA 测序表征其介质

König, Janine; Rokavec, Matjaz; Öner-Ziegler, Meryem Gülfem; Fei, Ye; Hermeking, Heiko

Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal cancer.

由于叉头框 A1 (FOXA1) 激活减少和 CpG 甲基化沉默导致 RBM47 下调,与结直肠癌的上皮-间质转化和转移有关。

Rokavec Matjaz, Du Yuyun, Hermeking Heiko

miRTARGET: An integrated web tool for the identification of microRNA targets with potential therapeutic or prognostic value in cancer

miRTARGET:一个用于识别在癌症中具有潜在治疗或预后价值的microRNA靶点的综合性网络工具

Rokavec, Matjaz; Hermeking, Heiko

AP4 induces JNK1 and a miR-22-3p/FOSL1 feed-forward loop to activate AP-1 and promote colorectal cancer metastasis

AP4诱导JNK1和miR-22-3p/FOSL1前馈环路激活AP-1并促进结直肠癌转移

Chou, Jinjiang; Kaller, Markus; Rokavec, Matjaz; Liu, Fangteng; Hermeking, Heiko

LINC01021 Attenuates Expression and Affects Alternative Splicing of a Subset of p53-Regulated Genes

LINC01021 减弱 p53 调控基因子集的表达并影响其可变剪接

Markus Kaller, Ignasi Forné, Axel Imhof, Heiko Hermeking

CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c in HCT116 colorectal cancer cells: comprehensive characterization after exposure to 5-FU reveals EMT and autophagy as key processes regulated by miR-34

CRISPR/Cas9 介导的 HCT116 结直肠癌细胞中 miR-34a 和 miR-34b/c 失活:暴露于 5-FU 后的全面表征揭示 EMT 和自噬是 miR-34 调控的关键过程

Zekai Huang, Markus Kaller, Heiko Hermeking

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis

姜黄素激活 ROS/KEAP1/NRF2/miR-34a/b/c 级联抑制结直肠癌转移

Chunfeng Liu, Matjaz Rokavec, Zekai Huang, Heiko Hermeking

Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with p53 mutation and elevated c- MYC expression

角鲨烯环氧酶/SQLE 是治疗伴有 p53 突变和 c-MYC 表达升高的结肠直肠癌的候选靶点

Yuyun Du, Matjaz Rokavec, Heiko Hermeking