日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Chelator Conjugation Chemistry Matters: Squaramide Linker Enhances Tumor Contrast in (68)Ga-labeled Anti-CEA Nanobody Tracer

螯合剂偶联化学至关重要：方酰胺连接子增强了 (68)Ga 标记的抗 CEA 纳米抗体示踪剂的肿瘤对比度

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c11686
Saliën, Jelena; Floru, Sam; Van Hove, Michiel; De Pauw, Tessa; Vizier, Romane; Claron, Michael; Bridoux, Jessica; Goncalves, Victor; Denat, Franck; Hernot, Sophie
肿瘤
肿瘤免疫
发表日期：2026
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A Comparative Study on the Effect of Near-Infrared Fluorescent Dyes on the Pharmacokinetic Behavior of Nanobody-Based Tracers for In Vivo Imaging

近红外荧光染料对基于纳米抗体的示踪剂在体内成像中的药代动力学行为影响的比较研究

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02376
Declerck, Noemi B; Declercq, Sofie; Debie, Pieterjan; Du Ville, Julie; Mateusiak, Łukasz; Saliën, Jelena; Stroet, Marcus C M; Luciano, Michael P; Li, Dong-Hao; Schnermann, Martin J; Smith, Bradley D; Hernot, Sophie
IF
发表日期：2025
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Molecular Tuning of Cyanine 5 Dyes to Improve the Pharmacokinetic Profile of Nanobody-Based Fluorescent Tracers

通过分子调控花菁5染料改善基于纳米抗体的荧光示踪剂的药代动力学特性

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00024
Mateusiak, Łukasz; Chigoho, Dora M; Floru, Sam; Pollenus, Sofie; Debie, Pieterjan; van Willigen, Danny M; van Leeuwen, Fijs W B; Hernot, Sophie
信号转导
IF
发表日期：2025
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Reflect: reporting guidelines for preclinical, translational and clinical fluorescence molecular imaging studies

反思：临床前、转化和临床荧光分子成像研究的报告指南

期刊:
影响因子:
doi:10.1038/s44303-025-00125-8
Keizers, Bas; Stroet, Marcus C M; Ali, Meedie; Floru, Sam; Saliën, Jelena; Mezzanotte, Laura; Delikatny, Edward J; Gibbs, Summer L; Giuliani, Stefano; Gioux, Sylvain; Ingelberts, Hans; Kruijff, Schelto; Ntziachristos, Vasilis; LaRochelle, Ethan; Rogalla, Stephan; Rosenthal, Eben L; Samkoe, Kimberley S; Tichauer, Kenneth M; Vahrmeijer, Alexander L; Witjes, Max J H; Voskuil, Floris J; Gorpas, Dimitris; Hernot, Sophie; van der Zaag, Pieter J
IF
发表日期：2025
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Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery

新型泛癌抗uPAR荧光纳米抗体的制备与表征及其在图像引导手术中的应用

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202400700
Mateusiak, Łukasz; Floru, Sam; De Groof, Timo W M; Wouters, Janne; Declerck, Noemi B; Debie, Pieterjan; Janssen, Simone; Zeven, Katty; Puttemans, Janik; Vincke, Cécile; Breckpot, Karine; Devoogdt, Nick; Hernot, Sophie
肿瘤
IF
肿瘤免疫
uPA
uPAR
发表日期：2024
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Plug-and-play nucleic acid-mediated multimerization of biparatopic nanobodies for molecular imaging

即插即用的核酸介导的双互补位纳米抗体多聚化用于分子成像

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.5
doi:10.1016/j.omtn.2024.102305
Laura Teodori, Sarah K Ochoa, Marjan Omer, Veronica L Andersen, Pernille Bech, Junyi Su, Jessica Bridoux, Jesper S Nielsen, Mathias B Bertelsen, Sophie Hernot, Kurt V Gothelf, Jørgen Kjems
信号转导
发表日期：2024
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Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting

单价纳米抗体针对巨噬细胞甘露糖受体的尺寸优势，可深入肿瘤穿透并靶向肿瘤相关巨噬细胞

期刊:Theranostics
影响因子:12.4
doi:10.7150/thno.77560
Marco Erreni, Francesca D'Autilia, Roberta Avigni, Evangelia Bolli, Sana M Arnouk, Kiavash Movahedi, Pieterjan Debie, Achille Anselmo, Raffaella Parente, Cécile Vincke, Fijs W B van Leeuwen, Paola Allavena, Cecilia Garlanda, Alberto Mantovani, Andrea Doni, Sophie Hernot, Jo A Van Ginderachter
肿瘤
巨噬细胞
发表日期：2023
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The GEM-handle as convenient labeling strategy for bimodal single-domain antibody-based tracers carrying (99m)Tc and a near-infrared fluorescent dye for intra-operative decision-making

GEM-handle 是一种便捷的标记策略，用于标记携带 (99m)Tc 和近红外荧光染料的双峰单域抗体示踪剂，以辅助术中决策。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2023.1285923
Declerck, Noemi B; Huygen, Celine; Mateusiak, Lukasz; Stroet, Marcus C M; Hernot, Sophie
IF
发表日期：2023
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Near-Infrared Fluorescence Imaging of Pancreatic Cancer Using a Fluorescently Labelled Anti-CEA Nanobody Probe: A Preclinical Study

使用荧光标记的抗 CEA 纳米抗体探针对胰腺癌进行近红外荧光成像：一项临床前研究

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom13040618
Labrinus van Manen, Lizzie D A N de Muynck, Victor M Baart, Shadhvi Bhairosingh, Pieterjan Debie, Alexander L Vahrmeijer, Sophie Hernot, J Sven D Mieog
代谢
肿瘤
胰腺癌
发表日期：2023
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Safety assessment of fluorescently labeled anti-EGFR Nanobodies in healthy dogs

荧光标记抗EGFR纳米抗体在健康犬中的安全性评估

期刊:Frontiers in Pharmacology
影响因子:4.4
doi:10.3389/fphar.2023.1266288
Nayra Cristina Herreira do Valle, Simone Janssen, Marcus C M Stroet, Sofie Pollenus, Sonja Van den Block, Nick Devoogdt, Jens M Debacker, Sophie Hernot #, Hilde De Rooster #
信号转导
ELISA
WB
HUTH
发表日期：2023
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