日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A population of naive-like CD4(+) T cells stably polarized to the T(H) 1 lineage

一群稳定极化为 T(H) 1 谱系的幼稚样 CD4(+) T 细胞

Lo, Jonathan W; de Mucha, Maria Vila; Henderson, Stephen; Roberts, Luke B; Constable, Laura E; Garrido-Mesa, Natividad; Hertweck, Arnulf; Stolarczyk, Emilie; Houlder, Emma L; Jackson, Ian; MacDonald, Andrew S; Powell, Nick; Neves, Joana F; Howard, Jane K; Jenner, Richard G; Lord, Graham M

A Crohn's Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling

克罗恩病相关的IL2RA增强子变体通过调节对IL-2信号的反应性来决定T细胞免疫的平衡

Goldberg, Rimma; Clough, Jennie N; Roberts, Luke B; Sanchez, Jenifer; Kordasti, Shahram; Petrov, Nedyalko; Hertweck, Arnulf; Lorenc, Anna; Jackson, Ian; Tasker, Scott; Appios, Anna; Omer, Omer; Parkes, Miles; Prescott, Natalie; Jenner, Richard G; Irving, Peter M; Lord, Graham M

The Th1 cell regulatory circuitry is largely conserved between human and mouse

Th1细胞调控回路在人和小鼠之间基本保守。

Henderson, Stephen; Pullabhatla, Venu; Hertweck, Arnulf; de Rinaldis, Emanuele; Herrero, Javier; Lord, Graham M; Jenner, Richard G

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

T-bet 通过介导因子和超延伸复合物激活 Th1 基因。

Hertweck, Arnulf; Evans, Catherine M; Eskandarpour, Malihe; Lau, Jonathan C H; Oleinika, Kristine; Jackson, Ian; Kelly, Audrey; Ambrose, John; Adamson, Peter; Cousins, David J; Lavender, Paul; Calder, Virginia L; Lord, Graham M; Jenner, Richard G

Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.

CD8 表达的负调控是通过 CD8 增强子介导的锌指蛋白 MAZR 的募集实现的

Bilic Ivan, Koesters Christina, Unger Bernd, Sekimata Masayuki, Hertweck Arnulf, Maschek Romana, Wilson Christopher B, Ellmeier Wilfried

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer

在缺乏 RNase III 酶 Dicer 的情况下,T 细胞谱系选择和分化

Cobb, Bradley S; Nesterova, Tatyana B; Thompson, Elizabeth; Hertweck, Arnulf; O'Connor, Eric; Godwin, Jonathan; Wilson, Christopher B; Brockdorff, Neil; Fisher, Amanda G; Smale, Stephen T; Merkenschlager, Matthias