日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase.

AMP激活蛋白激酶对网格蛋白介导的内吞作用进行货物选择性调节

Orofiamma Laura A, Delos Santos Ralph Christian, Mehrabi Ayshin, Leshchyshyn Nikol, Hesketh Geoffrey G, Rahmani Sadia, Patel Aesha, Fekri Farnaz, Ata Rehman, Ratcliffe Colin D H, Crupi Mathieu J F, Mulligan Lois, Park Morag, Gingras Anne-Claude, Antonescu Costin N

N-acetylglucosamine: more than a silent partner in insulin resistance

N-乙酰氨基葡萄糖:不仅仅是胰岛素抵抗的沉默伙伴

Hesketh, Geoffrey G; Dennis, James W

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

BLOC-1 和 BLOC-3 通过不同的管状运输载体调节 VAMP7 在黑素体中的循环。

Dennis, Megan K; Delevoye, Cédric; Acosta-Ruiz, Amanda; Hurbain, Ilse; Romao, Maryse; Hesketh, Geoffrey G; Goff, Philip S; Sviderskaya, Elena V; Bennett, Dorothy C; Luzio, J Paul; Galli, Thierry; Owen, David J; Raposo, Graça; Marks, Michael S

VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface

VARP 通过与逆转录酶直接相互作用而被募集到内体上,它们共同作用将 VARP 输出到细胞表面。

Hesketh, Geoffrey G; Pérez-Dorado, Inmaculada; Jackson, Lauren P; Wartosch, Lena; Schäfer, Ingmar B; Gray, Sally R; McCoy, Airlie J; Zeldin, Oliver B; Garman, Elspeth F; Harbour, Michael E; Evans, Philip R; Seaman, Matthew N J; Luzio, J Paul; Owen, David J

A mutation causing Brugada syndrome identifies a mechanism for altered autonomic and oxidant regulation of cardiac sodium currents.

导致布鲁加达综合征的突变揭示了心脏钠电流自主神经和氧化调节改变的机制

Aiba Takeshi, Farinelli Federica, Kostecki Geran, Hesketh Geoffrey G, Edwards David, Biswas Subrata, Tung Leslie, Tomaselli Gordon F

Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure

心脏再同步治疗可改善犬类不同步性心力衰竭模型中异常的钠通道门控功能

Aiba, Takeshi; Barth, Andreas S; Hesketh, Geoffrey G; Hashambhoy, Yasmin L; Chakir, Khalid; Tunin, Richard S; Greenstein, Joseph L; Winslow, Raimond L; Kass, David A; Tomaselli, Gordon F

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

Varp与VAMP7的结合使VAMP7处于一种封闭的、无融合活性的构象。

Schäfer, Ingmar B; Hesketh, Geoffrey G; Bright, Nicholas A; Gray, Sally R; Pryor, Paul R; Evans, Philip R; Luzio, J Paul; Owen, David J

Ultrastructure and regulation of lateralized connexin43 in the failing heart

衰竭心脏中侧向连接蛋白43的超微结构和调控

Hesketh, Geoffrey G; Shah, Manish H; Halperin, Victoria L; Cooke, Carol A; Akar, Fadi G; Yen, Timothy E; Kass, David A; Machamer, Carolyn E; Van Eyk, Jennifer E; Tomaselli, Gordon F

Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition

环磷酸鸟苷/PKG依赖性抑制TRPC6通道活性和表达负向调控心肌细胞NFAT活化;PDE5抑制调节心脏应激的新机制

Koitabashi, Norimichi; Aiba, Takeshi; Hesketh, Geoffrey G; Rowell, Janelle; Zhang, Manling; Takimoto, Eiki; Tomaselli, Gordon F; Kass, David A

IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers

IK1异质性影响心肌细胞单层螺旋波的产生和稳定性

Sekar, Rajesh B; Kizana, Eddy; Cho, Hee C; Molitoris, Jared M; Hesketh, Geoffrey G; Eaton, Brett P; Marbán, Eduardo; Tung, Leslie