日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Alzheimer's disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits.

阿尔茨海默病病理会破坏皮质-海马回路中 NMDA 受体依赖的自发活动模式。

Ellingford Robert, Harris Samuel S, Kehring Marten, Rajani Rikesh M, Lam Francesca Kar Wey, Graykowski David, BÓ§ken Dorothea, Welikovitch Lindsay A, Khasnavis Anita, Laban Rhiannon, Heslegrave Amanda, Yaman Umran, Mate de Gerando Anastasie, Bond Suraya A, Wray Selina, Salih Dervis A, Dupret David, Dolan Raymond J, Klenerman David, Zetterberg Henrik, Hyman Bradley T, Busche Marc Aurel

Mind the gap: obtaining reliable sleep estimates and the diagnostic value of sleep discrepancy in individuals with Alzheimer's disease and Lewy body disease

注意差距:获取可靠的睡眠评估结果以及睡眠差异在阿尔茨海默病和路易体病患者中的诊断价值

Gabb, Victoria Grace; Blackman, Jonathan; Morrison, Hamish Duncan; Turner, Nicholas; Heslegrave, Amanda; Coulthard, Elizabeth

Aging-related matrix metallopeptidase 10 and osteopontin levels are associated with pathology, cognitive decline, and age at onset in Alzheimer's disease

衰老相关的基质金属蛋白酶10和骨桥蛋白水平与阿尔茨海默病的病理、认知能力下降和发病年龄有关。

Ng, Bryan; Kodosaki, Eleftheria; Veleva, Elena; Keshavan, Ashvini; Schott, Jonathan M; Heslegrave, Amanda J; Fox, Nick C; Zetterberg, Henrik

The Alzheimer's Disease Diagnosis and Plasma Phospho-Tau217 (ADAPT) study stage 1: Validating clinical cut-points against CSF and amyloid PET

阿尔茨海默病诊断和血浆磷酸化Tau蛋白217 (ADAPT) 研究第一阶段:验证临床临界值与脑脊液和淀粉样蛋白PET的相关性

Keshavan, Ashvini; Wiltshire, Katharine; Wee, Ryan; Belio, Irene Gorostiaga; Tucker, Katie; Hart, Melanie; Lunn, Michael P; David, Michael C B; Rizzo, Laura; Sadeghi-Alavijeh, Omid; Wilson, Patricia; Gale, Daniel P; Heslegrave, Amanda J; Zetterberg, Henrik; Fox, Nick C; Malhotra, Paresh; Schott, Jonathan M

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

脑脊液中前脑啡肽水平可预测亨廷顿病患者纹状体萎缩,且早于临床运动症状的诊断数十年。

Farag, Mena; Murphy, Michael J; Hobbs, Nicola Z; Leocadi, Michela; Fayer, Kate; Thackeray, Olivia; Gobom, Johan; Ciosi, Marc; Heslegrave, Amanda; Zetterberg, Henrik; Langbehn, Douglas R; Monckton, Darren G; Wild, Edward J; Tabrizi, Sarah J; Scahill, Rachael I

Safety, efficacy, and distal nerve Schwann cell biodistribution in mice and NHPs to support translation of AAV9 RNAi therapy for CMT1A.

在小鼠和非人灵长类动物中评估 AAV9 RNAi 疗法治疗 CMT1A 的安全性、有效性和远端神经雪旺细胞生物分布,以支持其转化应用。

Stavrou Marina, Wallace Lindsay M, Thangaraj Merlin P, Taylor Noah K, Kagiava Alexia, Papacharalambous Revekka, McAllister Cynthia, Zender Gloria, Saad Nizar Y, Bayazit M Bilal, Heslegrave Amanda, Tryfonos Christina, Richter Jan, Zetterberg Henrik, Price Brian, Salzman Rachel, Kleopa Kleopas A, Harper Scott Q

Peripheral and CSF protein quantification in Parkinson's disease and multiple system atrophy-the nucleic acid-linked immuno-sandwich assay

帕金森病和多系统萎缩症患者外周血和脑脊液蛋白定量——核酸连接免疫夹心法

Vijiaratnam, Nirosen; Girges, Christine; Mitchell, Arthur; Athauda, Dilan; Fumi, Riona; Hay, Jennifer; O'Reilly, Nicola; Morris, Huw; Carroll, Camille; Hu, Michele T M; Silverdale, Monty A; Duncan, Gordon; Heslegrave, Amanda; Chai, Eliza; Gandhi, Sonia; Foltynie, Thomas

Blood-Brain Barrier Permeability in Cases of Post-operative Delirium Is Associated with Central Nervous System Phosphatidylcholine Imbalances

术后谵妄患者的血脑屏障通透性与中枢神经系统磷脂酰胆碱失衡有关

Jung, Mijin; Pan, Xiaobei; Sweeney, Aoife; Passmore, Anthony P; McGuinness, Bernadette; McAuley, Daniel F; Beverland, David; Heslegrave, Amanda J; Schott, Jonathan; Zetterberg, Henrik; Cunningham, Emma L; Green, Brian D

Pilot Study of Fingolimod Treatment in Neuronal Ceroid Lipofuscinosis Type 1

芬戈莫德治疗1型神经元蜡样脂褐质沉积症的初步研究

Messina, Martina; Whiteley, Rebecca; Gan, Chin; Heywood, Wendy E; Heslegrave, Amanda J; Keating, Megan; Taylor, Sophie; Footitt, Emma; Mills, Philippa; Hemingway, Cheryl; Gissen, Paul; Vecchiato, Katy

Systemic inflammation and its associations in acute moderate-severe Traumatic Brain Injury: a cross-sectional study

急性中重度创伤性脑损伤中的全身炎症及其相关性:一项横断面研究

Li, Lucia M; Kodosaki, Eleftheria; Xu, Chloe J Y; Heslegrave, Amanda; Zetterberg, Henrik; Graham, Neil S N; Zimmerman, Karl A; Garbero, Elena; Moro, Federico; Magnoni, Sandra; Bertolini, Guido; Loane, David J; Sharp, David J