日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.

利用高通量测量在不同环境下开发紧凑型转录效应因子

Tycko Josh, Van Mike V, Aradhana, DelRosso Nicole, Ye Hanrong, Yao David, Valbuena Raeline, Vaughan-Jackson Alun, Xu Xiaoshu, Ludwig Connor, Spees Kaitlyn, Liu Katherine, Gu Mingxin, Khare Venya, Mukund Adi Xiyal, Suzuki Peter H, Arana Sophia, Zhang Catherine, Du Peter P, Ornstein Thea S, Hess Gaelen T, Kamber Roarke A, Qi Lei S, Khalil Ahmad S, Bintu Lacramioara, Bassik Michael C

A High-Throughput Screen for Antiproliferative Peptides in Mammalian Cells Identifies Key Transcription Factor Families.

哺乳动物细胞抗增殖肽的高通量筛选鉴定出关键转录因子家族

Liila-Fogarty Shane M, Boyum Grace E, Schwabe Claire L, Hess Gaelen T

Transcriptomic signatures across human tissues identify functional rare genetic variation

跨人类组织的转录组特征可识别功能性罕见遗传变异

Ferraro, Nicole M; Strober, Benjamin J; Einson, Jonah; Abell, Nathan S; Aguet, Francois; Barbeira, Alvaro N; Brandt, Margot; Bucan, Maja; Castel, Stephane E; Davis, Joe R; Greenwald, Emily; Hess, Gaelen T; Hilliard, Austin T; Kember, Rachel L; Kotis, Bence; Park, YoSon; Peloso, Gina; Ramdas, Shweta; Scott, Alexandra J; Smail, Craig; Tsang, Emily K; Zekavat, Seyedeh M; Ziosi, Marcello; Aradhana; Ardlie, Kristin G; Assimes, Themistocles L; Bassik, Michael C; Brown, Christopher D; Correa, Adolfo; Hall, Ira; Im, Hae Kyung; Li, Xin; Natarajan, Pradeep; Lappalainen, Tuuli; Mohammadi, Pejman; Montgomery, Stephen B; Battle, Alexis

Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation

代谢精确标记能够选择性地探测 O-连接的 N-乙酰半乳糖胺糖基化

Debets, Marjoke F; Tastan, Omur Y; Wisnovsky, Simon P; Malaker, Stacy A; Angelis, Nikolaos; Moeckl, Leonhard K R; Choi, Junwon; Flynn, Helen; Wagner, Lauren J S; Bineva-Todd, Ganka; Antonopoulos, Aristotelis; Cioce, Anna; Browne, William M; Li, Zhen; Briggs, David C; Douglas, Holly L; Hess, Gaelen T; Agbay, Anthony J; Roustan, Chloe; Kjaer, Svend; Haslam, Stuart M; Snijders, Ambrosius P; Bassik, Michael C; Moerner, W E; Li, Vivian S W; Bertozzi, Carolyn R; Schumann, Benjamin

The impact of rare variation on gene expression across tissues

罕见变异对不同组织中基因表达的影响

Li, Xin; Kim, Yungil; Tsang, Emily K; Davis, Joe R; Damani, Farhan N; Chiang, Colby; Hess, Gaelen T; Zappala, Zachary; Strober, Benjamin J; Scott, Alexandra J; Li, Amy; Ganna, Andrea; Bassik, Michael C; Merker, Jason D; Hall, Ira M; Battle, Alexis; Montgomery, Stephen B

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

CRISPR介导的碱基编辑在真核生物基因组中的方法和应用

Hess, Gaelen T; Tycko, Josh; Yao, David; Bassik, Michael C

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

利用高通量筛选中Cas9毒性进行基因组规模的脱靶活性测量

Morgens, David W; Wainberg, Michael; Boyle, Evan A; Ursu, Oana; Araya, Carlos L; Tsui, C Kimberly; Haney, Michael S; Hess, Gaelen T; Han, Kyuho; Jeng, Edwin E; Li, Amy; Snyder, Michael P; Greenleaf, William J; Kundaje, Anshul; Bassik, Michael C

Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures

利用DNA对M13次要衣壳蛋白进行正交标记,使其自组装成端对端多噬菌体结构。

Hess, Gaelen T; Guimaraes, Carla P; Spooner, Eric; Ploegh, Hidde L; Belcher, Angela M

M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins

M13噬菌体展示框架,可实现通过分选酶介导对表面可及噬菌体蛋白进行修饰。

Hess, Gaelen T; Cragnolini, Juan J; Popp, Maximilian W; Allen, Mark A; Dougan, Stephanie K; Spooner, Eric; Ploegh, Hidde L; Belcher, Angela M; Guimaraes, Carla P

Cellular binding, motion, and internalization of synthetic gene delivery polymers

合成基因递送聚合物的细胞结合、运动和内化

Hess, Gaelen T; Humphries, William H 4th; Fay, Nicole C; Payne, Christine K