日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Genotoxic carcinogenicity of pyrrolizidine alkaloids: relevance of potency factors for the risk assessment

吡咯里西啶生物碱的遗传毒性致癌性：效力因子对风险评估的相关性

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-04182-1
Sachse, Benjamin; Hessel-Pras, Stefanie; Schäfer, Bernd
肿瘤
毒理研究
肿瘤免疫
发表日期：2026
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The pyrrolizidine alkaloid lasiocarpine impairs cell cycle progression in vitro

吡咯里西啶生物碱拉西卡品在体外会抑制细胞周期进程。

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-04185-y
Hessel-Pras, Stefanie; Beckschulte, Marlena; Peters, Antonia; Koellner, Anja; Rosskopp, Beatrice; Stahl, Aaron; Templin, Markus; Sprenger, Heike; Boehmert, Linda; Kuepper, Jan-Heiner; Sachse, Benjamin; Schaefer, Bernd
细胞生物学
发表日期：2025
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Results of the BfR MEAL Study: Acrylamide in foods from the German market with highest levels in vegetable crisps

德国联邦风险评估研究所 (BfR) 的 MEAL 研究结果：德国市场上食品中丙烯酰胺含量最高，其中蔬菜脆片含量最高。

期刊:Food Chemistry-X
影响因子:8.2
doi:10.1016/j.fochx.2024.101403
Perestrelo, Sara; Schwerbel, Kristin; Hessel-Pras, Stefanie; Schäfer, Bernd; Kaminski, Martin; Lindtner, Oliver; Sarvan, Irmela
发表日期：2024
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PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man

基于PBTK模型的CYP3A4诱导及吡咯里西啶生物碱雷特罗辛在人体内的毒代动力学分析

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-024-03698-2
Lehmann, Anja; Geburek, Ina; Hessel-Pras, Stefanie; Enge, Anne-Margarethe; Mielke, Hans; Müller-Graf, Christine; Kloft, Charlotte; Hethey, Christoph
BTK
CYP3A4
发表日期：2024
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Matrine and Oxymatrine: evaluating the gene mutation potential using in silico tools and the bacterial reverse mutation assay (Ames test)

苦参碱和氧化苦参碱：使用计算机工具和细菌回复突变试验（Ames 试验）评估基因突变潜力

期刊:Mutagenesis
影响因子:2.5
doi:10.1093/mutage/gead032
Benjamin Christian Fischer, Yemurai Musengi, Jeannette König, Benjamin Sachse, Stefanie Hessel-Pras, Bernd Schäfer, Carsten Kneuer, Kristin Herrmann
微生物学
发表日期：2024
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PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat

利用PBTK模型预测吡咯里西啶生物碱雷特罗辛在小鼠和大鼠中的肝毒性

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-023-03453-z
Lehmann, Anja; Geburek, Ina; These, Anja; Hessel-Pras, Stefanie; Hengstler, Jan G; Albrecht, Wiebke; Mielke, Hans; Müller-Graf, Christine; Yang, Xiaojing; Kloft, Charlotte; Hethey, Christoph
BTK
毒理研究
Rat
发表日期：2023
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Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose-response data

遗传毒性评估：剂量反应数据定量评价的机遇、挑战和展望

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-023-03553-w
Menz, Jakob; Götz, Mario E; Gündel, Ulrike; Gürtler, Rainer; Herrmann, Kristin; Hessel-Pras, Stefanie; Kneuer, Carsten; Kolrep, Franziska; Nitzsche, Dana; Pabel, Ulrike; Sachse, Benjamin; Schmeisser, Sebastian; Schumacher, David M; Schwerdtle, Tanja; Tralau, Tewes; Zellmer, Sebastian; Schäfer, Bernd
毒理研究
发表日期：2023
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Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro

体外吡咯里西啶生物碱的结构依赖性毒代动力学

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23169214
Buchmueller, Julia; Kaltner, Florian; Gottschalk, Christoph; Maares, Maria; Braeuning, Albert; Hessel-Pras, Stefanie
发表日期：2022
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Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study

吡咯里西啶生物碱诱导大鼠肺组织转录组变化的28天亚急性喂养研究

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-021-03108-x
Buchmueller, Julia; Sprenger, Heike; Ebmeyer, Johanna; Rasinger, Josef Daniel; Creutzenberg, Otto; Schaudien, Dirk; Hengstler, Jan G; Guenther, Georgia; Braeuning, Albert; Hessel-Pras, Stefanie
Rat
发表日期：2021
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Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

吡咯里西啶生物碱扰乱人肝癌细胞系HepaRG的胆汁酸稳态

期刊:Foods
影响因子:5.1
doi:10.3390/foods10010161
Waizenegger, Julia; Glück, Josephin; Henricsson, Marcus; Luckert, Claudia; Braeuning, Albert; Hessel-Pras, Stefanie
肿瘤
肿瘤免疫
Human
肝癌
细胞生物学
发表日期：2021
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