日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proximity labeling unveils potential roles of the Miro2-CISD1 network in mitochondrial dynamics and neuronal differentiation

邻近标记揭示了Miro2-CISD1网络在细胞线粒体动力学和神经元分化中的潜在作用

Kang, Im Kyeung; Lee, Sunwoo; Moon, Tae Kwon; Han, A Reum; Yu, Dae Bong; Jung, Minkyo; Kwak, Chulhwan; Seo, Jeong Kon; Rhee, Hyun-Woo; Kim, Seong Who; Woo, Ha-Na; Mun, Ji Young; Lee, Heuiran

DZ-1-artesunate conjugate induces mitochondria-mediated, reactive oxygen species-dependent apoptosis in colorectal cancer tumoroids

DZ-1-青蒿琥酯缀合物诱导结直肠癌类肿瘤细胞发生线粒体介导的、活性氧依赖性的细胞凋亡

Narayanasamy, Badrinath; Zhang, Yi; Gangi, Alexandra; Figlin, Robert; Sargsyan, Karine; Lee, Heuiran; Song, Cheryn; Lee, Yong J

Cross-species RNAi therapy via AAV delivery alleviates neuropathic pain by targeting GCH1.

通过 AAV 递送进行跨物种 RNAi 疗法,靶向 GCH1 可缓解神经性疼痛

Chang Heesue, Lee Kyoung Jin, Park Minkyung, Woo Ha-Na, Kim Ji Hyun, Kang Im Kyeung, Park Hyochan, Chon Chan Hee, Lee Heuiran, Jung Hyun Ho

Subretinal delivery of AAV5-mediated human Pde6b gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa

在视网膜色素变性大鼠模型中,视网膜下递送AAV5介导的人类Pde6b基因可改善疾病表型。

Kim, Hee Jong; Kwak, Ji Hoon; Choi, Jun Sub; Kim, Jin; Moon, Seo Yun; Lee, Steven Hyun Seung; Lee, Heuiran; Park, Keerang; Lee, Joo Yong; Won, So-Yoon

Integrative analysis of microRNA-mediated mitochondrial dysfunction in hippocampal neural progenitor cell death in relation with Alzheimer's disease

整合分析microRNA介导的线粒体功能障碍与海马神经祖细胞死亡的关系及其与阿尔茨海默病的关系

Han, A Reum; Moon, Tae Kwon; Kang, Im Kyeung; Yu, Dae Bong; Kim, Yechan; Byon, Cheolhwan; Park, Sujeong; Kim, Hae Lin; Kim, Hae Lin; Lee, Kyoung Jin; Lee, Heuiran; Woo, Ha-Na; Kim, Seong Who

mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy

mTOR 下调通过缺氧视网膜病变中的 CCL3-CCR5 轴促进抗炎反应

Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, A Reum Han, Ha-Na Woo, Joo Yong Lee, Jun-Sub Choi, Keerang Park, Heuiran Lee

A Single Injection of rAAV-shmTOR in Peripheral Nerve Persistently Attenuates Nerve Injury-Induced Mechanical Allodynia

外周神经单次注射 rAAV-shmTOR 可持续减轻神经损伤引起的机械性异常疼痛

Minkyung Park, Ha-Na Woo, Chin Su Koh, Heesue Chang, Ji Hyun Kim, Keerang Park, Jin Woo Chang, Heuiran Lee, Hyun Ho Jung

Microglial deactivation by adeno-associated virus expressing small-hairpin GCH1 has protective effects against neuropathic pain development in a spinothalamic tract-lesion model

腺相关病毒表达小发夹结构 GCH1 可使小胶质细胞失活,对脊髓丘脑束损伤模型中的神经性疼痛发展具有保护作用

Hyun Ho Jung, Chin Su Koh, Minkyung Park, Ji Hyun Kim, Ha-Na Woo, Heuiran Lee, Jin Woo Chang

mTOR inhibition as a novel gene therapeutic strategy for diabetic retinopathy

mTOR 抑制作为糖尿病视网膜病变的新型基因治疗策略

Steven Hyun Seung Lee, Joo Yong Lee, Jun-Sub Choi, Hee Jong Kim, Jin Kim, Seho Cha, Kyoung Jin Lee, Ha-Na Woo, Keerang Park, Heuiran Lee

AAV expressing an mTOR-inhibiting siRNA exhibits therapeutic potential in retinal vascular disorders by preserving endothelial integrity

表达 mTOR 抑制 siRNA 的 AAV 通过保持内皮完整性在视网膜血管疾病中表现出治疗潜力

Seho Cha, Won-Il Seo, Ha-Na Woo, Hee Jong Kim, Steven Hyun Seung Lee, Jin Kim, Jun-Sub Choi, Keerang Park, Joo Yong Lee, Beom Jun Lee, Heuiran Lee