日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Park7 deletion leads to sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes

Park7基因缺失导致小鼠中脑星形胶质细胞中NRF2-CYP1B1轴相关的性别特异性转录组变化

Sergio Helgueta ,Tony Heurtaux ,Alessia Sciortino ,Yujuan Gui ,Jochen Ohnmacht ,Pauline Mencke ,Ibrahim Boussaad ,Rashi Halder ,Pierre Garcia ,Rejko Krüger ,Michel Mittelbronn ,Manuel Buttini ,Thomas Sauter ,Lasse Sinkkonen

Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences.

THY-Tau22 小鼠 tau 蛋白病模型中的时间转录组变化表现出细胞类型和性别特异性差异

Ali Muhammad, Garcia Pierre, Lunkes Laetitia P, Sciortino Alessia, Thomas Melanie H, Heurtaux Tony, Grzyb Kamil, Halder Rashi, Skupin Alexander, Buée Luc, Blum David, Buttini Manuel, Glaab Enrico

Metabolic models predict fotemustine and the combination of eflornithine/rifamycin and adapalene/cannabidiol for the treatment of gliomas

代谢模型预测福莫司汀以及依氟鸟氨酸/利福霉素和阿达帕林/大麻二酚的组合可用于治疗神经胶质瘤。

Kishk, Ali; Pires Pacheco, Maria; Heurtaux, Tony; Sauter, Thomas

Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer's disease reveals sex-dependent dysregulations.

对阿尔茨海默病 THY-Tau22 小鼠模型的单细胞转录组分析揭示了性别依赖性失调

Ali Muhammad, Garcia Pierre, Lunkes Laetitia P, Sciortino Alessia, Thomas Melanie, Heurtaux Tony, Grzyb Kamil, Halder Rashi, Coowar Djalil, Skupin Alex, Buée Luc, Blum David, Buttini Manuel, Glaab Enrico

Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies

Tg2576小鼠的单细胞转录组分析和基因调控网络建模揭示了先于阿尔茨海默病样病理的性别依赖性分子特征

Ali, Muhammad; Huarte, Oihane Uriarte; Heurtaux, Tony; Garcia, Pierre; Rodriguez, Beatriz Pardo; Grzyb, Kamil; Halder, Rashi; Skupin, Alexander; Buttini, Manuel; Glaab, Enrico

Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease

纤维缺乏和微生物群导致的卷曲改变肠道细菌群落并加速帕金森病小鼠模型的疾病

Kristopher J Schmit, Pierre Garcia, Alessia Sciortino, Velma T E Aho, Beatriz Pardo Rodriguez, Mélanie H Thomas, Jean-Jacques Gérardy, Irati Bastero Acha, Rashi Halder, Camille Cialini, Tony Heurtaux, Irina Ostahi, Susheel B Busi, Léa Grandmougin, Tuesday Lowndes, Yogesh Singh, Eric C Martens, Miche

Normal and Pathological NRF2 Signalling in the Central Nervous System

中枢神经系统中正常和病理状态下的NRF2信号传导

Heurtaux, Tony; Bouvier, David S; Benani, Alexandre; Helgueta Romero, Sergio; Frauenknecht, Katrin B M; Mittelbronn, Michel; Sinkkonen, Lasse

Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease

在帕金森病的播种/扩散小鼠模型中,神经退行性和神经炎症相互关联,但与 α-突触核蛋白内含物无关

Pierre Garcia, Wiebke Jürgens-Wemheuer, Oihane Uriarte Huarte, Alessandro Michelucci, Annette Masuch, Simone Brioschi, Andreas Weihofen, Eric Koncina, Djalil Coowar, Tony Heurtaux, Enrico Glaab, Rudi Balling, Carole Sousa, Tony Kaoma, Nathalie Nicot, Tatjana Pfander, Walter Schulz-Schaeffer, Ahmad A

Apomorphine Reduces A53T α-Synuclein-Induced Microglial Reactivity Through Activation of NRF2 Signalling Pathway

阿扑吗啡通过激活 NRF2 信号通路降低 A53T α-突触核蛋白诱导的小胶质细胞反应性

Tony Heurtaux, Melanie Kirchmeyer, Eric Koncina, Paul Felten, Lorraine Richart, Oihane Uriarte Huarte, Herve Schohn, Michel Mittelbronn0

The Multifaceted Neurotoxicity of Astrocytes in Ageing and Age-Related Neurodegenerative Diseases: A Translational Perspective

星形胶质细胞在衰老和年龄相关神经退行性疾病中的多方面神经毒性:转化视角

Bouvier, David S; Fixemer, Sonja; Heurtaux, Tony; Jeannelle, Félicia; Frauenknecht, Katrin B M; Mittelbronn, Michel