日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural and Biochemical Characterization of Fusobacterium nucleatum Enoyl-ACP Reductase II (FabK) Reveals the Basis for Bacterial Species-Specific Inhibition

具核梭杆菌烯酰-ACP还原酶II (FabK) 的结构和生化表征揭示了细菌物种特异性抑制的基础

期刊:ACS Bio & Med Chem Au
影响因子:4.3
doi:10.1021/acsbiomedchemau.5c00199
Avad, Kristiana; Alaidi, Osama; Okpomo, Destiny; Pavel, Fahad Bin Aziz; Doran, Darcy; Matheson, Madeline; Sun, Dianqing; Hurdle, Julian; Hevener, Kirk E
微生物学
发表日期：2026
文献求助 收藏

In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy

苯基咪唑对艰难梭菌烯酰-ACP还原酶II (FabK) 抑制作用的体内评价揭示了一种有前景的窄谱抗菌策略

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01222-23
Dureja, Chetna; Rutherford, Jacob T; Pavel, Fahad B A; Norseeda, Krissada; Prah, Isaac; Sun, Dianqing; Hevener, Kirk E; Hurdle, Julian G
发表日期：2024
文献求助 收藏

Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor

简洁合成衣霉素V及发现一种细胞抑制性DPAGT1抑制剂

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202203225
Mitachi, Katsuhiko; Mingle, David; Effah, Wendy; Sánchez-Ruiz, Antonio; Hevener, Kirk E; Narayanan, Ramesh; Clemons, William M Jr; Sarabia, Francisco; Kurosu, Michio
细胞生物学
发表日期：2022
文献求助 收藏

Antibacterial kaneoheoic acids A-F from a Hawaiian fungus Fusarium sp. FM701.

从夏威夷真菌 Fusarium sp. FM701 中分离得到的抗菌烷醇酸 AF

期刊:Phytochemistry
影响因子:3.4
doi:10.1016/j.phytochem.2020.112545
Uz Zaman Kh Ahammad, Wu Xiaohua, Hu Zhenquan, Yoshida Wesley, Hou Shaobin, Saito Jennifer, Avad Kristiana Alexes, Hevener Kirk E, Alumasa John N, Cao Shugeng
其它
肠道菌群
发表日期：2021
文献求助 收藏

1233. Identification of Novel Inhibitors of Clostridioides difficile Enoyl-Reductase II (FabK) by High-Throughput Virtual and Experimental Screening

1233. 通过高通量虚拟和实验筛选鉴定艰难梭菌烯酰还原酶 II (FabK) 的新型抑制剂

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26115375
Leisawitz, Jacob P; He, Jiali; Baggeroer, Caroline; Hewett, Sandra J; Wahrmund, Rebecca D; Avad, Kristiana A; Reeve, Stephanie M; Jones, Jesse A; La, Thao; Lee, Richard E; Hevener, Kirk E
发表日期：2020
文献求助 收藏

The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection

脂肪酸合成蛋白烯酰-ACP还原酶II (FabK) 是治疗艰难梭菌感染的窄谱抗菌药物的靶点

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.8b00205
Marreddy, Ravi K R; Wu, Xiaoqian; Sapkota, Madhab; Prior, Allan M; Jones, Jesse A; Sun, Dianqing; Hevener, Kirk E; Hurdle, Julian G
代谢
炎症/感染
发表日期：2019
文献求助 收藏

Small-Molecule Inhibition of the C. difficile FAS-II Enzyme, FabK, Results in Selective Activity

小分子抑制剂对艰难梭菌FAS-II酶FabK的抑制作用导致选择性活性

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.9b00293
Jones, Jesse A; Prior, Allan M; Marreddy, Ravi K R; Wahrmund, Rebecca D; Hurdle, Julian G; Sun, Dianqing; Hevener, Kirk E
FAS
发表日期：2019
文献求助 收藏

The Vacuolar Ca(2+) ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis

液泡Ca(2+) ATPase泵Pmc1p是白色念珠菌致病所必需的

期刊:mSphere
影响因子:3.1
doi:10.1128/mSphere.00715-18
Luna-Tapia, Arturo; DeJarnette, Christian; Sansevere, Emily; Reitler, Parker; Butts, Arielle; Hevener, Kirk E; Palmer, Glen E
发表日期：2019
文献求助 收藏

Computational Toxicology Methods in Chemical Library Design and High-Throughput Screening Hit Validation

计算毒理学方法在化学库设计和高通量筛选先导化合物验证中的应用

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-4939-7899-1_13
Hevener, Kirk E
发表日期：2018
文献求助 收藏

Rifamycin Resistance in Clostridium difficile Is Generally Associated with a Low Fitness Burden

艰难梭菌的利福霉素耐药性通常与较低的适应性负担相关

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01137-16
Dang, Uyen T; Zamora, Idalia; Hevener, Kirk E; Adhikari, Sudip; Wu, Xiaoqian; Hurdle, Julian G
发表日期：2016
文献求助 收藏