Hewitt Nicola J相关文献与解析，生知库 | 链接生命科学的每一步

Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters

化学品安全评估分组：水杨酸酯毒代动力学特性的重要性

Najjar, Abdulkarim; Grégoire, Sébastien; Nicol, Beate; Natsch, Andreas; Golbamaki, Nazanin; Boisleve, Fanny; Irizar, Amaia; Wall, Brian; Swinscoe, Angus; Masini-Etévé, Valérie; Joshi, Kaushal; Api, Anne Marie; Griem, Peter; Reis, Allison; Hewitt, Nicola J; Cardamone, Estefania

发表日期：2025

文献求助收藏

Correction: Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters

更正：化学品安全评估分组：水杨酸酯毒代动力学特性的重要性

期刊:Archives of Toxicology

影响因子:6.9

doi:10.1007/s00204-025-04017-z

发表日期：2025

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A Novel Workflow for Non-Animal PBK Modelling of UV Filters: Oxybenzone as a Case Study

一种用于紫外线过滤剂非动物PBK建模的新型工作流程：以氧苯酮为例

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph18111607

Golbamaki, Nazanin; Moustié, Anne; Hewitt, Nicola J; Lereaux, Guillaume; Burbank, Matthew; Ben Yahya, El Mehdi; Grégoire, Sébastien; Roussel-Berlier, Laurène

发表日期：2025

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Physiological liver microtissue 384-well microplate system for preclinical hepatotoxicity assessment of therapeutic small molecule drugs.

用于治疗性小分子药物临床前肝毒性评估的生理性肝脏微组织 384 孔微孔板系统

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae123

FÃ¤s Lola, Chen Minjun, Tong Weida, Wenz Friederike, Hewitt Nicola J, Tu Monika, Sanchez Katarzyna, ZapiÃ³rkowska-Blumer Natalia, Varga Hajnalka, Kaczmarska Karolina, Colombo Maria Vittoria, Filippi Bruno G H

毒理研究

发表日期：2025

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Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure

下一代风险评估：一项从头开始的案例研究，旨在评估化妆品成分水杨酸苄酯经皮肤暴露后的全身安全性

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2024.1345992

Ebmeyer, Johanna; Najjar, Abdulkarim; Lange, Daniela; Boettcher, Mareike; Voß, Silja; Brandmair, Katrin; Meinhardt, Jaqueline; Kuehnl, Jochen; Hewitt, Nicola J; Krueger, Christopher-Tilman; Schepky, Andreas

发表日期：2024

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Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion

下一代风险评估交叉案例研究：应用十步框架推导润肤露中大豆苷元的安全浓度

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2024.1421601

Najjar, Abdulkarim; Kühnl, Jochen; Lange, Daniela; Géniès, Camille; Jacques, Carine; Fabian, Eric; Zifle, Anne; Hewitt, Nicola J; Schepky, Andreas

发表日期：2024

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Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data

更正：临时内部毒理学关注阈值（iTTC）的实际应用：基于临床数据的案例研究

期刊:Archives of Toxicology

影响因子:6.9

doi:10.1007/s00204-022-03398-9

Najjar, Abdulkarim; Ellison, Corie A; Gregoire, Sebastien; Hewitt, Nicola J

发表日期：2023

文献求助收藏

Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data

临时内部毒理学关注阈值（iTTC）的实际应用：基于临床数据的案例研究

期刊:Archives of Toxicology

影响因子:6.9

doi:10.1007/s00204-022-03371-6

Najjar, Abdulkarim; Ellison, Corie A; Gregoire, Sebastien; Hewitt, Nicola J

发表日期：2023

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ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application

通过局部给药，对3种高蛋白结合率的紫外线过滤剂进行ADME表征和PBK模型构建

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfad081

Li, Hequn; Bunglawala, Fazila; Hewitt, Nicola J; Pendlington, Ruth; Cubberley, Richard; Nicol, Beate; Spriggs, Sandrine; Baltazar, Maria; Cable, Sophie; Dent, Matthew

发表日期：2023

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Permeability of 16 Straight- and Branched-Chain Parabens Using the Caco-2 Assay

利用Caco-2细胞测定法测定16种直链和支链对羟基苯甲酸酯的渗透性

Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters

化学品安全评估分组：水杨酸酯毒代动力学特性的重要性

Correction: Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters

更正：化学品安全评估分组：水杨酸酯毒代动力学特性的重要性

A Novel Workflow for Non-Animal PBK Modelling of UV Filters: Oxybenzone as a Case Study

一种用于紫外线过滤剂非动物PBK建模的新型工作流程：以氧苯酮为例

Physiological liver microtissue 384-well microplate system for preclinical hepatotoxicity assessment of therapeutic small molecule drugs.

用于治疗性小分子药物临床前肝毒性评估的生理性肝脏微组织 384 孔微孔板系统

Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure

下一代风险评估：一项从头开始的案例研究，旨在评估化妆品成分水杨酸苄酯经皮肤暴露后的全身安全性

Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion

下一代风险评估交叉案例研究：应用十步框架推导润肤露中大豆苷元的安全浓度

Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data

更正：临时内部毒理学关注阈值（iTTC）的实际应用：基于临床数据的案例研究

Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data

临时内部毒理学关注阈值（iTTC）的实际应用：基于临床数据的案例研究

ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application

通过局部给药，对3种高蛋白结合率的紫外线过滤剂进行ADME表征和PBK模型构建