日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploring the potential of liver microphysiological systems of varied configurations to model cholestatic chemical effects.

探索不同配置的肝脏微生理系统在模拟胆汁淤积化学效应方面的潜力。

Nitsche Katharina S, Sakolish Courtney, Carmichael Paul L, Hewitt Philip, Bajaj Piyush, Ferguson Stephen S, Lloyd Sarah M, Wilson Sarah S, Bouwmeester Hans, Rusyn Ivan

An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs.

用于预测环境化学物质和药物肾脏清除率的体外-计算机模拟工作流程。

Sakolish Courtney, Lin Hsing-Chieh, Moyer Haley L, Ford Lucie C, Christen Charles H, Wetmore Barbara A, DeVito Michael J, Hewitt Philip, Ferguson Stephen S, Raad Farah, Rusyn Ivan, Chiu Weihsueh A

Short-Chain Fatty Acids Modulate Anti-ROR1 CAR T-Cell Function and Exhaustion in an Intestinal Adenocarcinoma-on-Chip Model.

短链脂肪酸在芯片肠腺癌模型中调节抗ROR1 CAR T细胞的功能和耗竭

Wegner Valentin D, Feile Adrian, Alb Miriam, Hudecek Michael, Hewitt Philip, Mosig Alexander S

Perspective of using in vitro models to understand immunotherapy-induced cytokine release syndrome

利用体外模型理解免疫疗法诱导的细胞因子释放综合征的视角

Perkins, Ethan; Cooper, Christopher; Lund, Emma; Alb, Miriam; Morgan, Hannah; Fogal, Birgit; Hewitt, Philip; Mazein, Alexander; Ostaszewski, Marek; Sewald, Katherina

Comparative analysis of Caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability.

在基于凝胶和膜的肠道通透性屏障模型中,对 Caco-2 细胞和人空肠及十二指肠类器官衍生细胞进行比较分析

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Ford Lucie C, Tsai Han-Hsuan D, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.

在 PhysioMimix T12 平台上,对不同来源的肾近端小管细胞在静态和流体条件下的生理和转运功能进行比较分析

Sakolish Courtney, Moyer Haley L, Tsai Han-Hsuan D, Ford Lucie C, Dickey Allison N, Bajaj Piyush, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Stanko Jason, Rusyn Ivan

Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity.

肾近端小管细胞来源在肾近端小管毒性体外研究中的比较分析

Sakolish Courtney, Tsai Han-Hsuan D, Lin Hsing-Chieh, Bajaj Piyush, Villenave Remi, Ferguson Stephen S, Stanko Jason P, Becker Richard A, Hewitt Philip, Chiu Weihsueh A, Rusyn Ivan

Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal(TM) Tissues in Membrane-Based Cultures with and Without Flow.

人类小肠组织模型评估屏障通透性:在有无流动条件下,对 Caco-2 细胞、空肠和十二指肠类器官衍生细胞以及 EpiIntestinal(TM) 组织在膜基培养中的比较分析

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Comparative Proteomic Characterization of Serum-Free Cultivated HepG2 Cells Reveals Upregulated Drug Metabolism and Increased Oxidative Stress Protection.

无血清培养的HepG2细胞的比较蛋白质组学表征揭示了药物代谢上调和氧化应激保护增强

Pfeifer Luisa-Marie, Singh Jasjot, Zimmer Aline, Krenkel Marc, Fischer Frank, Sensbach Janike, Pipp Frederic, Werkmann Daniela, Hewitt Philip

The evolving role of investigative toxicology in the pharmaceutical industry

调查毒理学在制药行业中不断演变的角色

Pognan, Francois; Beilmann, Mario; Boonen, Harrie C M; Czich, Andreas; Dear, Gordon; Hewitt, Philip; Mow, Tomas; Oinonen, Teija; Roth, Adrian; Steger-Hartmann, Thomas; Valentin, Jean-Pierre; Van Goethem, Freddy; Weaver, Richard J; Newham, Peter