日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dissecting Acute Drug-Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver-On-A-Chip Model

利用芯片肝脏模型,通过原代小鼠肝细胞和血细胞分析急性药物诱导的脂肪肝毒性及治疗反应

Liu, Hanyang; Yin, Guo; Kohlhepp, Marlene Sophia; Schumacher, Fabian; Hundertmark, Jana; Hassan, Mohamed I Abdelwahab; Heymann, Felix; Puengel, Tobias; Kleuser, Burkhard; Mosig, Alexander Sandy; Tacke, Frank; Guillot, Adrien

Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease

核受体在非酒精性脂肪肝疾病中连接代谢、炎症和纤维化

Puengel, Tobias; Liu, Hanyang; Guillot, Adrien; Heymann, Felix; Tacke, Frank; Peiseler, Moritz

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

外周血白细胞端粒缩短与接受免疫检查点抑制剂治疗的癌症患者生存率低相关

Rolles, Benjamin; Gorgulho, Joao; Tometten, Mareike; Roderburg, Christoph; Vieri, Margherita; Abels, Anne; Vucur, Mihael; Heymann, Felix; Tacke, Frank; Brümmendorf, Tim H; Luedde, Tom; Beier, Fabian; Loosen, Sven H

Polypropylene mesh implantation for hernia repair causes myeloid cell-driven persistent inflammation

用于疝修补术的聚丙烯网片植入会导致髓系细胞驱动的持续性炎症

Heymann, Felix; von Trotha, Klaus-Thilo; Preisinger, Christian; Lynen-Jansen, Petra; Roeth, Anjali A; Geiger, Melanie; Geisler, Lukas Jonathan; Frank, Anna Katharina; Conze, Joachim; Luedde, Tom; Trautwein, Christian; Binnebösel, Marcel; Neumann, Ulf P; Tacke, Frank

Isolation and time lapse microscopy of highly pure hepatic stellate cells

高纯度肝星状细胞的分离和延时显微镜观察

Bartneck, Matthias; Warzecha, Klaudia Theresa; Tag, Carmen Gabriele; Sauer-Lehnen, Sibille; Heymann, Felix; Trautwein, Christian; Weiskirchen, Ralf; Tacke, Frank

Long term intravital multiphoton microscopy imaging of immune cells in healthy and diseased liver using CXCR6.Gfp reporter mice

利用CXCR6.Gfp报告基因小鼠对健康和病变肝脏中的免疫细胞进行长期活体多光子显微成像

Heymann, Felix; Niemietz, Patricia M; Peusquens, Julia; Ergen, Can; Kohlhepp, Marlene; Mossanen, Jana C; Schneider, Carlo; Vogt, Michael; Tolba, Rene H; Trautwein, Christian; Martin, Christian; Tacke, Frank

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis

趋化因子受体CCR6依赖性的γδ T细胞在受损肝脏中的积累限制了肝脏炎症和纤维化

Hammerich, Linda; Bangen, Jörg M; Govaere, Olivier; Zimmermann, Henning W; Gassler, Nikolaus; Huss, Sebastian; Liedtke, Christian; Prinz, Immo; Lira, Sergio A; Luedde, Tom; Roskams, Tania; Trautwein, Christian; Heymann, Felix; Tacke, Frank

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice

在小鼠中,趋化因子受体CC基序趋化因子受体8介导了肝巨噬细胞的迁移和分化,而肝纤维化正是由该受体介导的。

Heymann, Felix; Hammerich, Linda; Storch, Dunja; Bartneck, Matthias; Huss, Sebastian; Rüsseler, Vanessa; Gassler, Nikolaus; Lira, Sergio A; Luedde, Tom; Trautwein, Christian; Tacke, Frank

Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria

肾树突状细胞在伴有蛋白尿的新月体肾小球肾炎中致病

Hochheiser, Katharina; Engel, Daniel R; Hammerich, Linda; Heymann, Felix; Knolle, Percy A; Panzer, Ulf; Kurts, Christian

The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis.

IL-23/Th17轴在实验性肾小球肾炎中促进肾损伤

Paust Hans-Joachim, Turner Jan-Eric, Steinmetz Oliver M, Peters Anett, Heymann Felix, Hölscher Christoph, Wolf Gunter, Kurts Christian, Mittrücker Hans-Willi, Stahl Rolf A K, Panzer Ulf