日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deep learning-based non-invasive profiling of tumor transcriptomes from cell-free DNA for precision oncology.

基于深度学习的无细胞DNA肿瘤转录组非侵入性分析,用于精准肿瘤学。

Patton Robert D, Netzley Alexander, Persse Thomas W, Nair Akira, Galipeau Patricia C, Coleman Ilsa M, Itagi Pushpa, Chandra Pooja, Adil Mohamed, Vashisth Manasvita, Sayar Erolcan, Hiatt Joseph B, Dumpit Ruth, Kollath Lori, Demirci Ridvan Arda, Ghodsi Alireza, Lam Hung-Ming, Morrissey Colm, Iravani Amir, Chen Delphine L, Hsieh Andrew C, MacPherson David, Haffner Michael C, Nelson Peter S, Ha Gavin

Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

单次注射伊匹木单抗联合纳武单抗后发生致命性肠神经丛病变:病例报告

Appelbaum, Jacob; Wells, David; Hiatt, Joseph B; Steinbach, Gideon; Stewart, F Marc; Thomas, Hannah; Nghiem, Paul; Kapur, Raj P; Thompson, John A; Bhatia, Shailender

Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes

对神经胶质瘤多个区域的深度测序揭示了临床相关基因突变的空间异质性

Kumar, Akash; Boyle, Evan A; Tokita, Mari; Mikheev, Andrei M; Sanger, Michelle C; Girard, Emily; Silber, John R; Gonzalez-Cuyar, Luis F; Hiatt, Joseph B; Adey, Andrew; Lee, Choli; Kitzman, Jacob O; Born, Donald E; Silbergeld, Daniel L; Olson, James M; Rostomily, Robert C; Shendure, Jay

The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line

非整倍体HeLa癌细胞系的单倍型解析基因组和表观基因组

Adey, Andrew; Burton, Joshua N; Kitzman, Jacob O; Hiatt, Joseph B; Lewis, Alexandra P; Martin, Beth K; Qiu, Ruolan; Lee, Choli; Shendure, Jay

Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.

通过高通量诱变鉴定的 E3 泛素连接酶活性增强突变

Starita Lea M, Pruneda Jonathan N, Lo Russell S, Fowler Douglas M, Kim Helen J, Hiatt Joseph B, Shendure Jay, Brzovic Peter S, Fields Stanley, Klevit Rachel E

Mammalian X upregulation is associated with enhanced transcription initiation, RNA half-life, and MOF-mediated H4K16 acetylation

哺乳动物X染色体上调与转录起始增强、RNA半衰期延长以及MOF介导的H4K16乙酰化有关。

Deng, Xinxian; Berletch, Joel B; Ma, Wenxiu; Nguyen, Di Kim; Hiatt, Joseph B; Noble, William S; Shendure, Jay; Disteche, Christine M

Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation

用于靶向、高精度检测低频变化的单分子分子反转探针

Hiatt, Joseph B; Pritchard, Colin C; Salipante, Stephen J; O'Roak, Brian J; Shendure, Jay

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

Assemblathon 2:评估三种脊椎动物的基因组从头组装方法

Bradnam, Keith R; Fass, Joseph N; Alexandrov, Anton; Baranay, Paul; Bechner, Michael; Birol, Inanç; Boisvert, Sébastien; Chapman, Jarrod A; Chapuis, Guillaume; Chikhi, Rayan; Chitsaz, Hamidreza; Chou, Wen-Chi; Corbeil, Jacques; Del Fabbro, Cristian; Docking, T Roderick; Durbin, Richard; Earl, Dent; Emrich, Scott; Fedotov, Pavel; Fonseca, Nuno A; Ganapathy, Ganeshkumar; Gibbs, Richard A; Gnerre, Sante; Godzaridis, Elénie; Goldstein, Steve; Haimel, Matthias; Hall, Giles; Haussler, David; Hiatt, Joseph B; Ho, Isaac Y; Howard, Jason; Hunt, Martin; Jackman, Shaun D; Jaffe, David B; Jarvis, Erich D; Jiang, Huaiyang; Kazakov, Sergey; Kersey, Paul J; Kitzman, Jacob O; Knight, James R; Koren, Sergey; Lam, Tak-Wah; Lavenier, Dominique; Laviolette, François; Li, Yingrui; Li, Zhenyu; Liu, Binghang; Liu, Yue; Luo, Ruibang; Maccallum, Iain; Macmanes, Matthew D; Maillet, Nicolas; Melnikov, Sergey; Naquin, Delphine; Ning, Zemin; Otto, Thomas D; Paten, Benedict; Paulo, Octávio S; Phillippy, Adam M; Pina-Martins, Francisco; Place, Michael; Przybylski, Dariusz; Qin, Xiang; Qu, Carson; Ribeiro, Filipe J; Richards, Stephen; Rokhsar, Daniel S; Ruby, J Graham; Scalabrin, Simone; Schatz, Michael C; Schwartz, David C; Sergushichev, Alexey; Sharpe, Ted; Shaw, Timothy I; Shendure, Jay; Shi, Yujian; Simpson, Jared T; Song, Henry; Tsarev, Fedor; Vezzi, Francesco; Vicedomini, Riccardo; Vieira, Bruno M; Wang, Jun; Worley, Kim C; Yin, Shuangye; Yiu, Siu-Ming; Yuan, Jianying; Zhang, Guojie; Zhang, Hao; Zhou, Shiguo; Korf, Ian F

Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders

多重靶向测序可识别自闭症谱系障碍中的复发性突变基因

O'Roak, Brian J; Vives, Laura; Fu, Wenqing; Egertson, Jarrett D; Stanaway, Ian B; Phelps, Ian G; Carvill, Gemma; Kumar, Akash; Lee, Choli; Ankenman, Katy; Munson, Jeff; Hiatt, Joseph B; Turner, Emily H; Levy, Roie; O'Day, Diana R; Krumm, Niklas; Coe, Bradley P; Martin, Beth K; Borenstein, Elhanan; Nickerson, Deborah A; Mefford, Heather C; Doherty, Dan; Akey, Joshua M; Bernier, Raphael; Eichler, Evan E; Shendure, Jay

Haplotype-resolved genome sequencing of a Gujarati Indian individual

对一名古吉拉特邦印度人进行单倍型解析基因组测序

Kitzman, Jacob O; Mackenzie, Alexandra P; Adey, Andrew; Hiatt, Joseph B; Patwardhan, Rupali P; Sudmant, Peter H; Ng, Sarah B; Alkan, Can; Qiu, Ruolan; Eichler, Evan E; Shendure, Jay