文献库，生知库 | 链接生命科学的每一步

日期影响因子

Resistance to the KRAS(G12D) Inhibitor MRTX1133 is Associated with Increased Sensitivity to BET Inhibition

对KRAS(G12D)抑制剂MRTX1133的耐药性与对BET抑制剂的敏感性增加相关

doi:10.1101/2025.05.10.653074

Principe, Daniel R; Becker, Jeffrey H; Metropulos, Anastasia E; Marinelarena, Alejandra M; Pham, Thao D; Aissa, Alexandre F; Munshi, Hidayatullah G

发表日期：2025

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Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer

以 BCL2 为靶点使用 Venetoclax 可增强 KRASG12D 抑制剂 MRTX1133 对胰腺癌的疗效

期刊:Cancer Research

影响因子:12.5

doi:10.1158/0008-5472.CAN-23-3574

Jeffrey H Becker #, Anastasia E Metropulos #, Christina Spaulding, Alejandra M Marinelarena, Mario A Shields, Daniel R Principe, Thao D Pham, Hidayatullah G Munshi

发表日期：2024

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BET Inhibition Rescues Acinar-Ductal-Metaplasia and Ciliogenesis and Ameliorates Chronic Pancreatitis-Driven Changes in Mice with Loss of the Polarity Protein Par3

BET 抑制可挽救腺泡导管化生和纤毛生成，并改善极性蛋白 Par3 缺失小鼠的慢性胰腺炎引发的变化

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.1

doi:10.1016/j.jcmgh.2024.101389

Mario A Shields, Anastasia E Metropulos, Christina Spaulding, Khulood A Alzahrani, Tomonori Hirose, Shigeo Ohno, Thao N D Pham, Hidayatullah G Munshi

发表日期：2024

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Trametinib Potentiates Anti-PD-1 Efficacy in Tumors Established from Chemotherapy-Primed Pancreatic Cancer Cells

曲美替尼可增强抗PD-1疗法对化疗预处理的胰腺癌细胞所建立的肿瘤的疗效

期刊:Molecular Cancer Therapeutics

影响因子:5.3

doi:10.1158/1535-7163.MCT-23-0833

Thao D Pham ，Anastasia E Metropulos # ，Nida Mubin # ，Jeffrey H Becker ，Dhavan Shah ，Christina Spaulding ，Mario A Shields ，David J Bentrem ，Hidayatullah G Munshi

细胞生物学

发表日期：2024

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Regorafenib induces DNA damage and enhances PARP inhibitor efficacy in pancreatic ductal carcinoma.

瑞戈非尼可诱导DNA损伤，并增强PARP抑制剂在胰腺导管癌中的疗效

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-024-13334-y

Pham Thao D, Becker Jeffrey H, Metropulos Anastasia E, Mubin Nida, Spaulding Christina, Bentrem David J, Munshi Hidayatullah G

发表日期：2024

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Loss of STK11 Suppresses Lipid Metabolism and Attenuates KRAS-Induced Immunogenicity in Patients with Non-Small Cell Lung Cancer

STK11缺失抑制脂质代谢并减弱非小细胞肺癌患者的KRAS诱导的免疫原性

期刊:Cancer Research Communications

影响因子:3.3

doi:10.1158/2767-9764.CRC-24-0153

Principe, Daniel R; Pasquinelli, Mary M; Nguyen, Ryan H; Munshi, Hidayatullah G; Hulbert, Alicia; Aissa, Alexandre F; Weinberg, Frank

细胞生物学

免疫/内分泌

发表日期：2024

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Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer

靶向 BET 蛋白可降低胰腺癌中的透明质酸酶-1

影响因子:5.1

doi:10.3390/cells12111490

Krishan Kumar, Deepak Kanojia, David J Bentrem, Rosa F Hwang, Jonathan P Butchar, Susheela Tridandapani, Hidayatullah G Munshi

发表日期：2023

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BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss

BET 抑制可挽救纤毛生成并改善 Par3 缺失小鼠的胰腺炎驱动表型变化

doi:10.1101/2023.09.14.557654

Mario A Shields, Anastasia E Metropulos, Christina Spaulding, Tomonori Hirose, Shigeo Ohno, Thao N D Pham, Hidayatullah G Munshi

发表日期：2023

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Richard Hynes, Erkki Ruoslahti, and Timothy Springer receive Lasker prize for pioneering work on integrins

Richard Hynes、Erkki Ruoslahti 和 Timothy Springer 因在整合素领域的开创性工作而荣获拉斯克奖。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI164374

Munshi, Hidayatullah G

发表日期：2022

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The immune modifying effects of chemotherapy and advances in chemo-immunotherapy

化疗的免疫调节作用及化疗免疫疗法的进展

期刊:Pharmacology & Therapeutics

影响因子:12.5

doi:10.1016/j.pharmthera.2022.108111

Principe, Daniel R; Kamath, Suneel D; Korc, Murray; Munshi, Hidayatullah G

免疫/内分泌

发表日期：2022

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