日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nanobody-Targeted Conditional Antimicrobial Therapeutics

纳米抗体靶向条件性抗菌疗法

Ngambenjawong, Chayanon; Ko, Henry; Samad, Tahoura; Pishesha, Novalia; Ploegh, Hidde L; Bhatia, Sangeeta N

A multivalent nanobody-drug conjugate to prevent and treat influenza virus infections

一种用于预防和治疗流感病毒感染的多价纳米抗体-药物偶联物

Harmand, Thibault J; Pietrok, Laura; Rich, Helen; Deshycka, Rhogerry; Flanagan, Laney; Accardo, Aaron; Pishesha, Novalia; Ploegh, Hidde L

A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses.

用扎那米韦修饰的单克隆抗血凝素茎抗体可预防甲型和乙型流感病毒感染

Liu Xin, Balligand Thomas, Le Gall Camille, Ploegh Hidde L

A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

利用抗转铁蛋白受体纳米抗体通过正电子发射断层扫描成像移植组织的一对同源小鼠

Thomas Balligand ,Claire Carpenet ,Sergi Olivé Palau ,Tom Jaspers ,Pavana Suresh ,Xin Liu ,Himadri Medhi ,Yoon Ho Lee ,Mohammad Rashidian ,Bart De Strooper ,Hidde L Ploegh ,Maarten Dewilde

Identification and characterization of nanobodies specific for the human ubiquitin-like ISG15 protein

鉴定和表征针对人泛素样蛋白ISG15的纳米抗体

Jin Gan,Prachi Dabhade,Charlotte Wijne,William McKibben,Simeon D Draganov,Hedib Alrawili,Zhen-Yu Jim Sun,Jack W Houghton,Edward W Tate,Camille Le Gall,Pavana Suresh,Novalia Pishesha,Adán Pinto-Fernández,Thomas U Schwartz,Hidde L Ploegh

A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes.

模块化的 Uba1-纳米抗体融合蛋白能够选择性地将泛素转移到标记的 E2 酶上。

Wijne Charlotte, D'Amico Francesca, Pérez Berrocal David A, Mulder Monique P C, Ploegh Hidde L, Gan Jin

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

拮抗性纳米抗体揭示了GSDMD孔道形成机制及其潜在的治疗应用。

Lisa D J Schiffelers ,Yonas M Tesfamariam ,Lea-Marie Jenster ,Stefan Diehl ,Sophie C Binder ,Sabine Normann ,Jonathan Mayr ,Steffen Pritzl ,Elena Hagelauer ,Anja Kopp ,Assaf Alon ,Matthias Geyer ,Hidde L Ploegh ,Florian I Schmidt

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

ESAT-6 在吞噬体 pH 下发生自缔合,ESAT-6 特异性纳米抗体限制结核分枝杆菌在巨噬细胞中的生长

Timothy A Bates, Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka, Shandee D Dixon, Anthony Shumate, Abigail R Groncki, Matthew A H Parson, Jessica R Ingram, Eric Barklis, John E Burke, Ujwal Shinde, Hidde L Ploegh, Fikadu G Tafesse

A monoclonal antibody that recognizes a unique 13-residue epitope in the cytoplasmic tail of HLA-E

一种单克隆抗体,可识别HLA-E胞质尾部独特的13个氨基酸残基的表位。

Elisha R Verhaar ,Jin Gan ,Susan Buhl ,Ziao Li ,Amir Horowitz ,Hidde L Ploegh

Nanobody-based CAR NK cells for possible immunotherapy of MICA+ tumors

基于纳米抗体的 CAR NK 细胞可能用于 MICA+ 肿瘤的免疫治疗

Elisha R Verhaar, Willemijn J C van Keizerswaard, Anouk Knoflook, Thomas Balligand, Hidde L Ploegh