日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS

CDCA7 的 C 端 4CXXC 型锌指结构域可识别半甲基化的 DNA 并调节染色质重塑酶 HELLS 的活性

Akeo Shinkai, Hideharu Hashimoto, Chikako Shimura, Hiroaki Fujimoto, Kei Fukuda, Naoki Horikoshi, Masaki Okano, Hitoshi Niwa, Erik W Debler, Hitoshi Kurumizaka, Yoichi Shinkai

Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids

两种 DOT1 酶协同介导动质体中有效的泛素依赖性组蛋白 H3 赖氨酸 76 三甲基化

Victoria S Frisbie #, Hideharu Hashimoto #, Yixuan Xie, Francisca N De Luna Vitorino, Josue Baeza, Tam Nguyen, Zhangerjiao Yuan, Janna Kiselar, Benjamin A Garcia, Erik W Debler

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates

不同的机制控制 p53 对与不同细胞命运相关的靶基因的基因组识别

Marina Farkas, Hideharu Hashimoto, Yingtao Bi, Ramana V Davuluri, Lois Resnick-Silverman, James J Manfredi, Erik W Debler, Steven B McMahon

Distinctive Klf4 mutants determine preference for DNA methylation status

独特的 Klf4 突变体决定 DNA 甲基化状态的偏好

Hideharu Hashimoto, Dongxue Wang, Alyse N Steves, Peng Jin, Robert M Blumenthal, Xing Zhang, Xiaodong Cheng

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA

耐格里阿米巴四联体样双加氧酶与5-甲基胞嘧啶DNA复合物的结构

Hideharu Hashimoto ,June E Pais ,Xing Zhang ,Lana Saleh ,Zheng-Qing Fu ,Nan Dai ,Ivan R Corrêa Jr ,Yu Zheng ,Xiaodong Cheng

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells

针对癌症(包括癌症干细胞)中活跃的人类 DNA 甲基转移酶的选择性非核苷抑制剂

Sergio Valente, Yiwei Liu, Michael Schnekenburger, Clemens Zwergel, Sandro Cosconati, Christina Gros, Maria Tardugno, Donatella Labella, Cristina Florean, Steven Minden, Hideharu Hashimoto, Yanqi Chang, Xing Zhang, Gilbert Kirsch, Ettore Novellino, Paola B Arimondo, Evelina Miele, Elisabetta Ferrett

Structural basis for human PHF2 Jumonji domain interaction with metal ions

人类 PHF2 Jumonji 结构域与金属离子相互作用的结构基础

John R Horton, Anup K Upadhyay, Hideharu Hashimoto, Xing Zhang, Xiaodong Cheng