Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing.
在 Cas9 介导的基因组编辑过程中，通过瞬时双重抑制 TP53 和 DNA 甲基化，高效地在雌性 hPSC 中重新激活 XIST
期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04501-4
Motosugi Nami, Hasegawa Keita, Kurosaki Natsumi, Kawaguchi Erika, Izumi Kenji, Iida Yumi, Higashiseto Misaki, Yokoyama Keiko, Sasaki Ayumi, Nakabayashi Kazuhiko, Fukuda Atsushi
