TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
TBX2 抑制 CST6,导致不受控制的 legumain 活性,从而维持乳腺癌细胞增殖:一种具有治疗机会的新型癌症选择性靶向通路
期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.1707
D'Costa Zenobia C, Higgins Catherine, Ong Chee Wee, Irwin Gareth W, Boyle David, McArt Darragh G, McCloskey Karen, Buckley Niamh E, Crawford Nyree T, Thiagarajan Lalitha, Murray James T, Kennedy Richard D, Mulligan Karl A, Harkin D Paul, Waugh David J J, Scott Chris J, Salto-Tellez Manuel, Williams Richard, Mullan Paul B