日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular definition of the endogenous Toll-like receptor signalling pathways.

内源性 Toll 样受体信号通路的分子定义。

Fisch Daniel, Zhang Tian, Sun He, Ma Weiyi, Tan Yunhao, Gygi Steven P, Higgins Darren E, Kagan Jonathan C

The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes

巨噬细胞中的液泡途径在由包裹在脂质体中的成孔蛋白Sticholysin II诱导的抗原交叉呈递中起着重要作用

Cruz-Leal, Yoelys; Grubaugh, Daniel; Nogueira, Catarina V; Lopetegui-González, Isbel; Del Valle, Anaixis; Escalona, Felipe; Laborde, Rady J; Alvarez, Carlos; Fernández, Luis E; Starnbach, Michael N; Higgins, Darren E; Lanio, María E

Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin

单核细胞增生李斯特菌入侵大脑是由InlF和宿主细胞波形蛋白介导的。

Ghosh, Pallab; Halvorsen, Elizabeth M; Ammendolia, Dustin A; Mor-Vaknin, Nirit; O'Riordan, Mary X D; Brumell, John H; Markovitz, David M; Higgins, Darren E

Novel Adjuvant Based on the Pore-Forming Protein Sticholysin II Encapsulated into Liposomes Effectively Enhances the Antigen-Specific CTL-Mediated Immune Response

一种基于成孔蛋白Sticholysin II的新型佐剂,通过脂质体包裹,可有效增强抗原特异性CTL介导的免疫反应。

Laborde, Rady J; Sanchez-Ferras, Oraly; Luzardo, María C; Cruz-Leal, Yoelys; Fernández, Audry; Mesa, Circe; Oliver, Liliana; Canet, Liem; Abreu-Butin, Liane; Nogueira, Catarina V; Tejuca, Mayra; Pazos, Fabiola; Álvarez, Carlos; Alonso, María E; Longo-Maugéri, Ieda M; Starnbach, Michael N; Higgins, Darren E; Fernández, Luis E; Lanio, María E

The diaphanous-related formins promote protrusion formation and cell-to-cell spread of Listeria monocytogenes.

与 diaphanous 相关的 formin 促进单核细胞增生李斯特菌的突起形成和细胞间传播

Fattouh Ramzi, Kwon Hyunwoo, Czuczman Mark A, Copeland John W, Pelletier Laurence, Quinlan Margot E, Muise Aleixo M, Higgins Darren E, Brumell John H

T(H)17-based vaccine design for prevention of Streptococcus pneumoniae colonization

基于T(H)17的疫苗设计用于预防肺炎链球菌定植

Moffitt, Kristin L; Gierahn, Todd M; Lu, Ying-jie; Gouveia, Paulo; Alderson, Mark; Flechtner, Jessica Baker; Higgins, Darren E; Malley, Richard

Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection

李斯特菌溶素O抑制磷脂酶C介导的杀菌性NADPH氧化酶的激活,从而促进单核细胞增生李斯特菌的感染。

Lam, Grace Y; Fattouh, Ramzi; Muise, Aleixo M; Grinstein, Sergio; Higgins, Darren E; Brumell, John H

A small-molecule screen identifies the antipsychotic drug pimozide as an inhibitor of Listeria monocytogenes infection

小分子筛选发现抗精神病药物匹莫齐特可抑制单核细胞增生李斯特菌感染。

Lieberman, Linda A; Higgins, Darren E

Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes.

抑制 ROCK 活性可使 InlF 介导的侵袭和单核细胞增生李斯特菌的毒力增强

Kirchner Marieluise, Higgins Darren E

Flagellar motility is critical for Listeria monocytogenes biofilm formation

鞭毛运动对于单核细胞增生李斯特菌生物膜的形成至关重要。

Lemon, Katherine P; Higgins, Darren E; Kolter, Roberto