日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacological approaches to understanding protein kinase signaling networks

利用药理学方法理解蛋白激酶信号网络

Stephenson, Elloise H; Higgins, Jonathan M G

CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation.

CDK1介导的H2B丝氨酸6位点的磷酸化是细胞有丝分裂染色体分离所必需的

Seibert Markus, Krüger Marcus, Watson Nikolaus A, Sen Onur, Daum John R, Slotman Johan A, Braun Thomas, Houtsmuller Adriaan B, Gorbsky Gary J, Jacob Ralf, Kracht Michael, Higgins Jonathan M G, Schmitz M Lienhard

Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis

Polo样激酶-1在有丝分裂中通过Haspin触发组蛋白磷酸化

Zhou, Linli; Tian, Xiaoying; Zhu, Cailei; Wang, Fangwei; Higgins, Jonathan M G

Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres

Survivin旁系同源物在内着丝粒处对组蛋白H3尾部进行磷酸化特异性识别的分子基础

Niedzialkowska, Ewa; Wang, Fangwei; Porebski, Przemyslaw J; Minor, Wladek; Higgins, Jonathan M G; Stukenberg, P Todd

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

β-咔啉衍生物作为haspin激酶抑制剂的构效关系研究

Cuny, Gregory D; Ulyanova, Natalia P; Patnaik, Debasis; Liu, Ji-Feng; Lin, Xiangjie; Auerbach, Ken; Ray, Soumya S; Xian, Jun; Glicksman, Marcie A; Stein, Ross L; Higgins, Jonathan M G

A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis

Haspin 和 Aurora B 参与的正反馈回路促进有丝分裂过程中着丝粒处 CPC 的积累。

Wang, Fangwei; Ulyanova, Natalia P; van der Waal, Maike S; Patnaik, Debasis; Lens, Susanne M A; Higgins, Jonathan M G

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?

通过抑制组蛋白乙酰转移酶扰乱有丝分裂:赭曲霉毒素A毒性和致癌性的关键?

Czakai, Kristin; Müller, Katja; Mosesso, Pasquale; Pepe, Gaetano; Schulze, Markus; Gohla, Antje; Patnaik, Debasis; Dekant, Wolfgang; Higgins, Jonathan M G; Mally, Angela

Haspin: a newly discovered regulator of mitotic chromosome behavior

Haspin:一种新发现的有丝分裂染色体行为调节因子

Higgins, Jonathan M G

The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility

钙黏蛋白-11胞质近膜结构域促进黏附连接处α-连环蛋白的周转和细胞间运动。

Kiener, Hans P; Stipp, Christopher S; Allen, Philip G; Higgins, Jonathan M G; Brenner, Michael B

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment

激酶 haspin 是组蛋白 H3 Thr 3 位点磷酸化和正常中期染色体排列所必需的。

Dai, Jun; Sultan, Sammy; Taylor, Stephen S; Higgins, Jonathan M G