Higgins Paul J相关文献与解析，生知库 | 链接生命科学的每一步

Targeted Interference with USF2 Binding to the SERPINE1 Proximal Promoter E-Box in Dual Mutant p53(R282Q,H179Y) Human Keratinocytes Inhibits Serum-/TGF-β1-Induced SERPINE1 Expression and Stimulates Epithelial Cell Proliferation

在双突变体p53(R282Q,H179Y)人角质形成细胞中，靶向干扰USF2与SERPINE1近端启动子E-box的结合可抑制血清/TGF-β1诱导的SERPINE1表达并刺激上皮细胞增殖。

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines14030726

Higgins, Stephen P; Czekay, Ralf-Peter; Higgins, Craig E; Higgins, Paul J

SEPT9 and PAI-1 are immunohistochemical biomarkers of the hepatocellular carcinoma immune microenvironment

SEPT9 和 PAI-1 是肝细胞癌免疫微环境的免疫组织化学生物标志物。

期刊:Discover Oncology

影响因子:2.9

doi:10.1007/s12672-025-02252-5

Park, Eundong; Wang, Xin; Subasi, Nusret Bekir; Kmeid, Michel; Higgins, Paul J; Chen, Anne; Lee, Hwajeong

SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment

SERPINE1：在胆管癌进展中的作用以及促纤维增生微环境中的治疗靶点

期刊:Cells

影响因子:5.2

doi:10.3390/cells13100796

Czekay, Ralf-Peter; Higgins, Craig E; Aydin, Hasan Basri; Samarakoon, Rohan; Subasi, Nusret Bekir; Higgins, Stephen P; Lee, Hwajeong; Higgins, Paul J

Emerging Role of Hippo-YAP (Yes-Associated Protein)/TAZ (Transcriptional Coactivator with PDZ-Binding Motif) Pathway Dysregulation in Renal Cell Carcinoma Progression

Hippo-YAP（Yes相关蛋白）/TAZ（具有PDZ结合基序的转录共激活因子）通路失调在肾细胞癌进展中的新兴作用

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers16152758

Mondal, Varsha; Higgins, Paul J; Samarakoon, Rohan

Downstream Targets of VHL/HIF-α Signaling in Renal Clear Cell Carcinoma Progression: Mechanisms and Therapeutic Relevance

肾透明细胞癌进展中VHL/HIF-α信号通路下游靶点：机制及治疗意义

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers15041316

Mazumder, Sonia; Higgins, Paul J; Samarakoon, Rohan

Mineralocorticoid Receptor-Associated Mechanisms in Diabetic Kidney Disease and Clinical Significance of Mineralocorticoid Receptor Antagonists

糖尿病肾病中盐皮质激素受体相关机制及盐皮质激素受体拮抗剂的临床意义

期刊:American Journal of Nephrology

影响因子:3.2

doi:10.1159/000528783

Mende, Christian W; Samarakoon, Rohan; Higgins, Paul J

Emerging role of tumor suppressor p53 in acute and chronic kidney diseases

肿瘤抑制因子p53在急性和慢性肾脏疾病中的新兴作用

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-022-04505-w

Overstreet, Jessica M; Gifford, Cody C; Tang, Jiaqi; Higgins, Paul J; Samarakoon, Rohan

Editorial: The Role of Steroid Hormones and Growth Factors in Cancer

社论：类固醇激素和生长因子在癌症中的作用

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.3

doi:10.3389/fcell.2022.887529

Cernera, Gustavo; Di Donato, Marzia; Higgins, Paul J; Schlaepfer, Isabel R

Potential renal stem/progenitor cells identified by in vivo lineage tracing

通过体内谱系追踪鉴定出潜在的肾脏干/祖细胞

期刊:

影响因子:

doi:10.1152/ajprenal.00326.2021

Zhang, Wenzheng; Gao, Chao; Tsilosani, Akaki; Samarakoon, Rohan; Plews, Robert; Higgins, Paul J

细胞生物学

发表日期：2022

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Involvement of c-Myc/WWP1/TRIM65 Axis in Renal Fibrosis.

c-Myc/WWP1/TRIM65轴参与肾纤维化。

Targeted Interference with USF2 Binding to the SERPINE1 Proximal Promoter E-Box in Dual Mutant p53(R282Q,H179Y) Human Keratinocytes Inhibits Serum-/TGF-β1-Induced SERPINE1 Expression and Stimulates Epithelial Cell Proliferation

在双突变体p53(R282Q,H179Y)人角质形成细胞中，靶向干扰USF2与SERPINE1近端启动子E-box的结合可抑制血清/TGF-β1诱导的SERPINE1表达并刺激上皮细胞增殖。

SEPT9 and PAI-1 are immunohistochemical biomarkers of the hepatocellular carcinoma immune microenvironment

SEPT9 和 PAI-1 是肝细胞癌免疫微环境的免疫组织化学生物标志物。

SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment

SERPINE1：在胆管癌进展中的作用以及促纤维增生微环境中的治疗靶点

Emerging Role of Hippo-YAP (Yes-Associated Protein)/TAZ (Transcriptional Coactivator with PDZ-Binding Motif) Pathway Dysregulation in Renal Cell Carcinoma Progression

Hippo-YAP（Yes相关蛋白）/TAZ（具有PDZ结合基序的转录共激活因子）通路失调在肾细胞癌进展中的新兴作用

Downstream Targets of VHL/HIF-α Signaling in Renal Clear Cell Carcinoma Progression: Mechanisms and Therapeutic Relevance

肾透明细胞癌进展中VHL/HIF-α信号通路下游靶点：机制及治疗意义

Mineralocorticoid Receptor-Associated Mechanisms in Diabetic Kidney Disease and Clinical Significance of Mineralocorticoid Receptor Antagonists

糖尿病肾病中盐皮质激素受体相关机制及盐皮质激素受体拮抗剂的临床意义

Emerging role of tumor suppressor p53 in acute and chronic kidney diseases

肿瘤抑制因子p53在急性和慢性肾脏疾病中的新兴作用

Editorial: The Role of Steroid Hormones and Growth Factors in Cancer

社论：类固醇激素和生长因子在癌症中的作用

Potential renal stem/progenitor cells identified by in vivo lineage tracing

通过体内谱系追踪鉴定出潜在的肾脏干/祖细胞