日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers.

抗 CSF-1R 疗法与免疫化疗相结合,可协调适应性免疫反应,以消除富含巨噬细胞的三阴性乳腺癌。

Pedroza Diego A, Yuan Xueying, Liu Fengshuo, Chan Hilda L, Zhang Christina, Bowie William, Smith Alex J, Calderon Sebastian J, Lieu Nadia, Wu Weiguo, Porter Paul, Sarkar Poonam, Zhao Na, Oehler Constanze V, Peller Ondrej, Gaber M Waleed, Zhu Qian, Perou Charles M, Zhang Xiang H-F, Rosen Jeffrey M

Inflammation- and resolution-programmed myeloid circuits govern therapeutic resistance in epithelial and mesenchymal triple-negative breast cancer

炎症和消退程序性髓系回路调控上皮性和间质性三阴性乳腺癌的治疗耐药性

Yu, Liqun; Rivas, Charlotte; Liu, Fengshuo; Shen, Yichao; Wu, Ling; Xu, Zhan; Ding, Yunfeng; Hao, Xiaoxin; Zhang, Weijie; Chan, Hilda L; Liu, Jun; Wei, Bo; Gao, Yang; Becerra-Dominguez, Luis; Wu, Yi-Hsuan; Wang, Siyue; Lee, Tobie D; Li, Xuan; Chen, Xiang; Edwards, David G; Zhang, Xiang H-F

Adolescent mortality in Lebanon (2017-2022): Trends, causes, and policy implications

黎巴嫩青少年死亡率(2017-2022):趋势、原因和政策启示

Naja, Cyrine; Al-Hajj, Samar; Sakr, Carine; Harb, Hilda L; Adib, Salim M

Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer

肿瘤来源的花生四烯酸可重编程中性粒细胞,从而促进三阴性乳腺癌的免疫抑制和治疗耐药性

Liqun Yu ,Keziah Liebenberg ,Yichao Shen ,Fengshuo Liu ,Zhan Xu ,Xiaoxin Hao ,Ling Wu ,Weijie Zhang ,Hilda L Chan ,Bo Wei ,Philip L Lorenzi ,Yang Gao ,Igor Bado ,Luis Becerra-Dominguez ,Charlotte Helena Rivas ,Sergio Aguirre ,Bradley C Pingel ,Yi-Hsuan Wu ,Yunfeng Ding ,Jun Liu ,David G Edwards ,Livia S Eberlin ,Xiang H-F Zhang

Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization

对多种癌症类型骨转移生态系统的单细胞分析揭示了骨定植的趋同和分歧机制

Fengshuo Liu ,Yunfeng Ding ,Zhan Xu ,Xiaoxin Hao ,Tianhong Pan ,George Miles ,Siyue Wang ,Yi-Hsuan Wu ,Jun Liu ,Igor L Bado ,Weijie Zhang ,Ling Wu ,Yang Gao ,Liqun Yu ,David G Edwards ,Hilda L Chan ,Sergio Aguirre ,Michael Warren Dieffenbach ,Elina Chen ,Yichao Shen ,Dane Hoffman ,Luis Becerra Dominguez ,Charlotte Helena Rivas ,Xiang Chen ,Hai Wang ,Zbigniew Gugala ,Robert L Satcher ,Xiang H-F Zhang

Anti-CSF-1R therapy with combined immuno- chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched Triple Negative Breast Cancers.

抗 CSF-1R 疗法与免疫化疗相结合,可协调适应性免疫反应,以消除富含巨噬细胞的三阴性乳腺癌

Pedroza Diego A, Yuan Xueying, Liu Fengshuo, Chan Hilda L, Zhang Christina, Bowie William, Smith Alex J, Calderon Sebastian J, Lieu Nadia, Wu Weiguo, Porter Paul, Sarkar Poonam, Zhao Na, Oehler Constanze V, Peller Ondrej, Gaber M Waleed, Zhu Qian, Perou Charles M, Zhang Xiang H-F, Rosen Jeffrey M

Solid tumour-induced systemic immunosuppression involves dichotomous myeloid-B cell interactions

实体瘤引起的全身免疫抑制涉及髓系细胞和B细胞之间的二元相互作用。

Xiaoxin Hao # ,Yichao Shen # ,Jun Liu ,Angela Alexander ,Ling Wu ,Zhan Xu ,Liqun Yu ,Yang Gao ,Fengshuo Liu ,Hilda L Chan ,Che-Hsing Li ,Yunfeng Ding ,Weijie Zhang ,David G Edwards ,Nan Chen ,Azadeh Nasrazadani ,Naoto T Ueno ,Bora Lim ,Xiang H-F Zhang

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer

CREB结合蛋白/P300溴结构域抑制剂可减少中性粒细胞聚集并激活三阴性乳腺癌的抗肿瘤免疫

Xueying Yuan ,Xiaoxin Hao ,Hilda L Chan ,Na Zhao ,Diego A Pedroza ,Fengshuo Liu ,Kang Le ,Alex J Smith ,Sebastian J Calderon ,Nadia Lieu ,Michael J Soth ,Philip Jones ,Xiang Hf Zhang ,Jeffrey M Rosen

CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC

CBP/P300 BRD 抑制剂可减少中性粒细胞积聚并激活 TNBC 中的抗肿瘤免疫

Xueying Yuan, Xiaoxin Hao, Hilda L Chan, Na Zhao, Diego A Pedroza, Fengshuo Liu, Kang Le, Alex J Smith, Sebastian J Calderon, Nadia Lieu, Michael J Soth, Philip Jones, Xiang H-F Zhang, Jeffrey M Rosen

Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal

骨祖细胞-GMP 相互作用是实体瘤诱导全身免疫抑制的基础,并且在肿瘤切除后仍然存在。

Xiaoxin Hao ,Yichao Shen ,Nan Chen ,Weijie Zhang ,Elizabeth Valverde ,Ling Wu ,Hilda L Chan ,Zhan Xu ,Liqun Yu ,Yang Gao ,Igor Bado ,Laura Natalee Michie ,Charlotte Helena Rivas ,Luis Becerra Dominguez ,Sergio Aguirre ,Bradley C Pingel ,Yi-Hsuan Wu ,Fengshuo Liu ,Yunfeng Ding ,David G Edwards ,Jun Liu ,Angela Alexander ,Naoto T Ueno ,Po-Ren Hsueh ,Chih-Yen Tu ,Liang-Chih Liu ,Shu-Hsia Chen ,Mien-Chie Hung ,Bora Lim ,Xiang H-F Zhang