日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The impact of Asic2 deletion on metabolic homeostasis in mice.

Asic2 缺失对小鼠代谢稳态的影响

Hamby Madison, Kaur Jasleen, Lirette Seth, do Carmo Jussara M, Speed Joshua, Islam Tawhida, Hildebrandt Emily, Barr Elizabeth, Challagundala Lavanya, Drummond Heather A

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

五肽序列作为蛋白质法尼基转移酶底物的文库筛选、体内验证、结构和生物信息学分析

Schey, Garrett L; Hildebrandt, Emily R; Wang, You; Diwan, Safwan; Passetti, Holly A; Potts, Gavin W; Sprague-Getsy, Andrea M; Leoni, Ethan R; Kuebler, Taylor S; Sham, Yuk Y; Hougland, James L; Beese, Lorena S; Schmidt, Walter K; Distefano, Mark D

Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential.

通过靶向基因和小分子手段破坏 N-Ras CaaX 的切割,可以改变其定位和致癌潜力

Hildebrandt Emily R, Hussain Shaneela A, Sieburg Michelle A, Ravishankar Rajani, Asad Nadeem, Gore Sangram, Ito Takahiro, Hougland James L, Dore Timothy M, Schmidt Walter K

Comprehensive analysis of CXXX sequence space reveals that Saccharomyces cerevisiae GGTase-I mainly relies on a2X substrate determinants

对 CXXX 序列空间的全面分析表明,酿酒酵母 GGTase-I 主要依赖于 a2X 底物决定簇。

Sarkar, Anushka; Hildebrandt, Emily R; Patel, Khushi V; Mai, Emily T; Shah, Sumil A; Kim, June H; Schmidt, Walter K

Comprehensive analysis of CXXX sequence space reveals that S. cerevisiae GGTase-I mainly relies on a(2)X substrate determinants

对 CXXX 序列空间的全面分析表明,酿酒酵母 GGTase-I 主要依赖于 a(2)X 底物决定簇。

Sarkar, Anushka; Hildebrandt, Emily R; Patel, Khushi V; Mai, Emily T; Shah, Sumil S; Kim, June H; Schmidt, Walter K

A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences

对酵母法尼基转移酶活性的全面体内筛选表明,其对大多数CXXX序列具有广泛的反应性。

Kim, June H; Hildebrandt, Emily R; Sarkar, Anushka; Yeung, Wayland; Waldon, La Ryel A; Kannan, Natarajan; Schmidt, Walter K

MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase

MALDI-MS分析肽库拓展了法尼基转移酶的底物范围

Schey, Garrett L; Buttery, Peter H; Hildebrandt, Emily R; Novak, Sadie X; Schmidt, Walter K; Hougland, James L; Distefano, Mark D

Interleukin-17 induces hypertension but does not impair cerebrovascular function in pregnant rats

白细胞介素-17可诱发妊娠大鼠高血压,但不损害其脑血管功能。

Duncan, Jeremy W; Nemeth, Zoltan; Hildebrandt, Emily; Granger, Joey P; Ryan, Michael J; Drummond, Heather A

Pressure-induced constriction of the middle cerebral artery is abolished in TrpC6 knockout mice

在TrpC6基因敲除小鼠中,压力诱导的大脑中动脉收缩现象消失。

Nemeth, Zoltan; Hildebrandt, Emily; Ryan, Michael J; Granger, Joey P; Drummond, Heather A

Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences

蛋白质法尼基转移酶催化缩短靶序列的非预期法尼基化和香叶基香叶基化

Ashok, Sudhat; Hildebrandt, Emily R; Ruiz, Colby S; Hardgrove, Daniel S; Coreno, David W; Schmidt, Walter K; Hougland, James L