Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation.
工程化的 BMP2/BMP7 细胞外囊泡诱导自分泌 BMP 释放,驱动 SMAD 磷酸化,从而促进骨形成
期刊:npj Regenerative Medicine
影响因子:6.5
doi:10.1038/s41536-025-00405-2
Du Zeji, Rizzo Skylar A, Sarrafian Tiffany L, Bagwell Monique S, Mahlberg Ryan C, Amontree Ashley, Schiebel Paige, Tauferner Dinah M, LeBrasseur Zoe S, Witt Tyra A, Nagel Mary, Boyd Kyla A, De Vitto Humberto, Hillestad Matthew L, Stalboerger Paul G, Houdek Matthew T, Sierra Rafael J, Behfar Atta